Griffonia Simplicifolia Seed Extract

Griffonia Simplicifolia Seed Extract — 98% 5-HTP Powder for Mood, Sleep & Weight Management Formulas

Shaanxi Hongda Phytochemistry Co., Ltd. is a certified manufacturer and supplier of Griffonia Simplicifolia Seed Extract, standardised to 98% 5-HTP by HPLC. It’s an off-white powder that’s a direct serotonin precursor or precursor to serotonin that is able to penetrate the blood-brain barrier. It’s sourced from Griffonia simplicifolia seeds produced in West Africa. Hongda boasts an annual output of 3,000 tons, 100,000-level purification workshops, and cGMP, FSSC22000, KOSHER, HALAL, VEGAN, and ORGANIC (EU/NOP) Certifications, ensuring batch-to-batch quality for dietary supplement, nootropic, and weight management applications. Ships in 2-3 working days from ready stock.

Product Introduction

Griffonia Simplicifolia Seed Extract is a botanical extract from the seeds of the woody climbing shrub Griffonia simplicifolia, a species endemic to Ghana and Ivory Coast. Its main active ingredient is L-5-Hydroxytryptophan (5-HTP), which is a direct biochemical precursor of serotonin (5-HT).

This plant source provides natural L-isomer 5-HTP with higher bio-compatibility and a proven “Peak X-free” profile, a vital safety standard not met by synthetic tryptophan. Eosinophilia-Myalgia Syndrome (EMS) has been associated with Peak X contamination and it is still a major regulatory issue for the US and EU markets.

The extract is a pale grey to off-white powder with a faint herbal odour and a bitter taste. Slightly soluble in water, soluble in hot alcohol. M.P., about 270°.

Griffonia Simplicifolia Seed Specification

Third-Party Testing

Shaanxi Hongda manufactures each batch internally and with third-party verification. Internal testing utilises HPLC, UV spectrophotometer and GC equipment. The external testing is carried out by laboratories SGS and Eurofins.

The following checks are necessary before shipping:

· HPLC Assay - indicates ≥98.0% 5-HTP on a dry basis

· Peak X Screening — confirms absence of cytotoxic contaminants related to EMS

Solvent Residue Analysis – verified no Class 1 or 2 solvents utilised; only ethanol and water utilised

· Heavy Metal Profiling — ICP-MS testing for Pb, As, Cd and Hg under 10 ppm total

· Pesticide Residue Detection – Meets Proposition 65 and EU Food Safety requirements

· Microbiological Testing – total plate count, yeast and mould, and pathogen screening

Full COA, MSDS and 3rd Party Test Reports available upon request.

Key Advantages

Not synthetic racemic natural L-isomer.The plant-derived 5-HTP’s chirality profile suggests higher biological compatibility than synthetic mixes – a key feature for clean-label positioning.

Peak X-Free verified.This is a non-negotiable requirement for US and EU compliance. Each batch is tested and documentation provided.

Thermal stability up to 120 °CThe extract is stable to pasteurisation and extrusion processes and can therefore be incorporated into functional food formats, such as meal replacement bars and shakes.

95% will pass an 80 mesh sieve.Consistent particle size provides reliable blendability and flowability throughout the manufacture of capsules and tablets.

Multiple certifications on one source.KOSHER, HALAL, VEGAN, ORGANIC (EU/NOP) and cGMP all under one roof lowers your vendor complexity.

Application Areas

This extract is utilised in three main B2B formulation categories:

1. Dietary Supplements for Mood and Sleep

Active substance used in capsules and tablets for emotional balance and sound sleep. To match the flow of excipients like magnesium stearate, the powder needs to be granulated and must be stable in test under compression.

2. Functional Foods in Weight Management

Used as a satiety agent in meal replacement shakes and bars. Formulators must consider the bitter taste profile (masking agents are usually used) and demonstrate thermal stability by extrusion or pasteurisation up to 120°C.

3. Nootropic & Synergistic Mixes

Often used in combination with GABA or Melatonin or L-Theanine. Stability against decarboxylation and resistance to hygroscopic clumping when mixed with adaptogenic substances are important quality requirements in these complicated blends.

Production Process

Shaanxi Hongda employs a controlled multi-stage extraction process:

Raw Material Selection → Cleaning & Drying → Solvent Extraction (Ethanol/Water) → Filtration & Concentration → Purification & Standardisation → Spray Drying → Sieving (80 mesh) → QC Testing → Packaging

All production is carried out in 100,000-level clean rooms. Solvent use is confined to ethanol and water (no methanol, benzene or Class 1/2 solvents) for compliance with all USP and EP monograph standards.

Why Choose Shaanxi Hongda?

· More than 20 years plant extract production experience since 2001

• Annual production of 3000 tons - enough supply for bulk purchase

• 20,000 m2 plant with 10+ contemporary production lines and 100,000+ level clean rooms

• SGS in-house laboratory standardised with 20+ years experienced R&D and QC staff

* 2-3 working days delivery from ready stock * Supports courier, air and ocean freight

• Complete documentation support - COA, MSDS, third party reports, nutritional labels, reports of natural origin

OEM / ODM Support

Shaanxi Hongda can offer comprehensive customisation manufacture according to your formula specifications. Formats include:

· Hard capsules and soft capsules

· Tablets and compressed tablets

· Pre-mixed powders and powders on demand

· private label packaging with your own trademark

You can request unique specs like 20%, 50%, or 99% 5-HTP for cost-sensitive or luxury product lines. Minimum order quantities and lead times are confirmed at the enquiry stage. All custom items are manufactured in cGMP certified circumstances and can be certified KOSHER, HALAL and ORGANIC if necessary.

FAQ

Q1: What is the regular specification of your product?

A: Our standard product is HPLC certified 98% 5-HTP. We also have 20%, 50% and 99% grades to fit your formulation and budget needs.

Q2: Is the extraction technique solvent-based?

A: The extraction is done using ethanol and water alone. No Class 1 or 2 solvents such as methanol or benzene. Each batch report contains solvent residue testing.

Q3: How do you test to ensure the product is Peak X free?

A: Every batch is tested for contaminants, especially Peak X pollutants. This test result is part of the third-party report and COA shipped with.

Q4: Does your product have a certification?

Q: What certifications do you now hold? A: ISO9001, FSSC22000, cGMP, KOSHER, HALAL, VEGAN, FDA registration, ORGANIC (EU), ORGANIC (NOP)

Q5: Can you customise 5-HTP content or private label packaging?

A: Yes, Shaanxi Hongda is able to provide OEM/ODM service for custom assay level, formulation format and package design. Reach out to us to talk about your project needs.

Q6: What are the storage conditions and shelf life?

A: Keep in a sealed container in a cool, dry area away from direct light. Shelf life 24 months under recommended storage conditions. Packaging: in a fibre drum, net 25kg/unit, double-layer PE bag.

Contact Us

Do you have more questions about Griffonia Simplicifolia Seed Extract? Get a quote or request a free sample today — email us at duke@hongdaherb.com.