Hidrosmin Powder

Premium Hidrosmin Powder - Manufacturer & Supplier | Shaanxi Hongda Phytochemistry

Our Hidrosmin Powder is unmatched on the market for increased bioavailability and better water solubility than typical diosmin products. We control the whole production process from the cultivation of raw materials in our certified planting bases to the final testing in our SGS-standardized laboratory, so that you might get a consistent and high-purity product that fulfils worldwide pharmaceutical standards. Manufactured with more than 20 years of experience, state-of-the-art extraction equipment and Certifications like cGMP, FSSC22000, ISO9001, HALAL and KOSHER, providing a reliable product to help your formulations reach a faster therapeutic onset and greater patient compliance. With our annual manufacturing capacity of 3,000 tonnes and smooth logistics, we can deliver on time for your business needs.

Product Introduction

Product is a semi-synthetic flavonoid synthesised from Citrus Aurantium L., a modification of diosmin through specialised synthesis using chlorosulfonic acid reaction and alkaline hydrolysis. This pharmaceutical quality raw material is a yellow to yellow brown fine powder with good water solubility, which basically solves the bioavailability problem of the ordinary diosmin. Our product criteria is 85% purity by HPLC CAS number 115960-14-0 The improved hydrophilic qualities allow a quick dissolving in aqueous media, thus it is useful in different pharmacological preparations aimed at supporting the venous health and microcirculation.​​​​​​​

Third-Party Test Report

SGS Authentication: Our product is tested thoroughly by SGS, one of the most recognised third-party testing agencies in the world for authenticity, purity levels and non-adulteration.

Eurofins Pesticide Residue Analysis: We collaborate with Eurofins laboratories to conduct multi-residue pesticide screening covering over 500 compounds, ensuring your product meets EU and FDA regulatory standards for Pharmaceutical Ingredients.

Heavy Metal Screening: Lead, arsenic, cadmium and mercury are tested by independent laboratories using ICP-MS technology and all findings are under the limits set by USP <232> and Ph.Eur. 2.4.27.

Certificate of Analysis (COA)

Hidrosmin Powder Advantages

Enhanced Bioavailability: Molecular engineering adds hydrophilic groups that boost water solubility exponentially, making micronization unnecessary and achieving absorption rates 3-4 times greater than typical diosmin formulations.

Rapid Therapeutic Effect: Your formulations show a much shorter Tmax (time to peak plasma concentration), leading to speedier symptom alleviation in patients with venous insufficiency. This characteristic is particularly advantageous in acute therapy regimens.

Formulation Flexibility: Our powder can be easily formulated into aqueous-based systems such as gels, syrups and liquid-filled capsules, without the precipitation problems that limit formulation options with poorly soluble flavonoids.

Hidrosmin Powder Application

Chronic Venous Insufficiency Treatment: Serves as the primary Active Pharmaceutical Ingredient in oral formulations targeting edema reduction, heavy leg sensation, and nighttime cramps by strengthening venous walls and improving microcirculation.

Management of Acute Haemorrhoidal Crisis: Designed in high-dosage loading therapies where quick absorption becomes crucial, offering fast-acting relief from pain, oedema, and bleeding in acute haemorrhoidal episodes.

Topical Therapeutic Preparations: Uniquely suited for transdermal gel formulations treating superficial phlebitis and traumatic bruising, where its exceptional water solubility enables stable hydrophilic gel matrices that penetrate the stratum corneum effectively.

Production Process

Step 1 - Raw Material Selection: We carefully source premium Citrus Aurantium L. from our certified organic planting base, where professional agronomists monitor growth conditions. Result: Only fruits of the highest degree of ripeness and purity are pressed.

Step 2 - Diosmin Extraction: The raw components are treated by modern enzymatic extraction and column chromatography purification in our 100,000-level clean workshop. Result: Base material of diosmin with high purity, HPLC proved purity > 90%.

Step 3 - Chemical Modification: The purified dioxmin is reacted with chlorosulfonic acid under regulated temperature and pH settings, and then is subjected to exact alkaline hydrolysis in specialised reactors. Result: Structural change generates the hydrophilic hydroxyl groups characteristic of the product.

Step 4 - Purification & Crystallisation: The reaction mixture is purified by multi-stage recrystallisation and activated carbon decolorisation to eliminate unreacted intermediates and impurities. Result: 85%+ purity specification pharmaceutical grade crystal powder.

Step 5 - Drying & Milling: The crystals are spray dried under vacuum and processed using precision equipment to obtain a homogeneous particle size distribution. Free flowing powder having improved dissolving rate and tableting capabilities.

OEM/ODM Support

Custom Formulation Development: Our team of 20+ Ph.D.-level scientists in R&D work together with you to create exclusive Hidrosmin Powder formulations with supplementary compounds such as hesperidin, rutin or vitamin C that are optimised for your desired therapeutic results.

Flexible Dosage Forms: We create to your unique requirements in hard capsules (vegetarian or gelatin), tablets (immediate or sustained-release), sachets with pre-mixed powders and topical gel bases, all within our cGMP-certified facility.

Private Label Packaging: We supply a wide variety of packaging options include bulk pharmaceutical packaging in 25kg fibre drums to retail ready bottles with your brand design, blister packs, aluminium foil sachets and custom labelling that satisfy regional regulatory standards.

Why Choose Us?

Shaanxi Hongda Phytochemistry represents more than two decades of excellence in natural plant extract manufacturing. Our vertically integrated enterprise with certified organic planting bases and cutting edge extraction facilities with HPLC, GC-MS and UV spectrophotometry. Our devotion to quality has gained us the trust of our clients in Europe, North America and Asia, with prestigious certifications including cGMP, FSSC22000, ISO9001, ISO22000, HALAL, KOSHER and ORGANIC (EU/NOP). Our factory covers an area of 20,000 square meters and is equipped with numerous manufacturing lines and national patent technology 100,000-level purification workshop. With a staff of 150+ technicians and 20+ Ph.D. researchers, we offer complete solutions, not simply raw materials. We provide fast customer service, reliable logistics with 3-7 day delivery, and versatile customisation capabilities, making us your ideal long-term partner. When you pick Hongda, you are choosing pharmaceutical-grade quality, scientific innovation and a transparent and results-oriented business partnership.

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FAQ

Q: What is the difference between the product and conventional Diosmin?

A: The fundamental difference is chemical alteration to increase water solubility by adding hydrophilic groups. This leads to better bioavailability and quicker absorption without the need for micronization.

Q: What’s the MOQ for your product? A: The MOQ is 100 pcs.

A: We accept all order sizes, from sample quantities (100g) to wholesale orders. Our general packaging for commercial production is 25kg per fibre drum with various quantity options.

Q: Can you give us samples for test before bulk purchase?

A: Yes! We provide samples (20-100g) packed in aluminium foil pouches so you can undertake quality control and formulation testing prior to placing larger purchases.

Contact Us

Ready to elevate your pharmaceutical or nutraceutical formulations with premium Hidrosmin Powder?

Email: duke@hongdaherb.com