L-Rhamnose Monohydrate

L-Rhamnose Monohydrate 98% | Natural Plant-Derived Sugar | Pharma & Cosmetic Grade

The company Shaanxi Hongda Phytochemistry Co., Ltd. makes and sells L-Rhamnose Monohydrate, which comes from Sophora japonica and is made by breaking down Rutin in acid. Hongda has 20,000m² production facilities, 10+ modern production lines, and a yearly output of 3,000 tonnes. They offer pharmaceutical-grade quality that is backed by Certifications like KOSHER, HALAL, BRC, ORGANIC, ISO9001, and ISO22000, as well as HPLC testing that confirms 98% purity and ≥99% optical purity. The delivery is done between 3 and 7 business days. You can get the raw materials you need from Hongda, whether you need to make flavour synthesis, anti-aging products, or chiral pharmaceutical intermediates.​​​​​​​

Product Introduction

The chemical formula for L-Rhamnose Monohydrate is C₆H₁O₅·H₂O, and its molecular weight is 182.17 g/mol. It is a naturally occurring 6-deoxy-L-mannose.

It forms a white powder when acid breaks down Rutin or Quercetin, and it comes from the Sophora japonica plant. This plant source ensures aL-configuration that synthetic routes alone can't match.

Because of its L-chirality, it is a very popular building block in the fields of flavour chemistry, dermo-cosmetic formulations, and pharmaceutical synthesis.

Third-Party Test Report

There are tests done on every batch of products both in-house and by authorised third-party labs.

Hongda Shaanxi's in-house lab is SGS-certified and has HPLC, GC, UV spectrophotometers, atomic absorption spectrophotometers, and polarimeters. Before any shipment leaves the facility, these instruments check for heavy metals, microbial safety, specific optical rotation, assay purity, and the amount of moisture.

Independent checks are done by SGS and Eurofins, and they check for pesticide residues, nutrition labels, and reports on natural sources. You can ask for full test documentation at any point in the buying process.

COA (Certificate of Analysis)

Every package comes with a full COA for that batch that includes:

Test: >98.0% by HPLC

Optically, it rotates between +7.8° and +8.3° (identity confirmation against D-isomers).

9.0% to 11.0% if it dries out (proving stoichiometric monohydrate status).

Remaining on Ignition: ≤0.1%

Heavy Metals and Arsenic: Within the limits set by USP and EP

How it dissolves: It forms a clear, colourless solution in water, which shows that there are no polymeric impurities present.

Microscopic: Meets international guidelines for food and drug safety

Before making your order, please get in touch with us to ask for a sample COA or a product specification sheet.

L-Rhamnose Monohydrate Advantages

Stable Crystalline Form

The form that is only monohydrate is physically stable when stored in the usual way. Anhydrous rhamnose easily takes water from the air and forms clumps, but this form stays stable in handling and stoichiometric accuracy in formulations.

Checked for Chiral Purity

Certain visual rotation tests (+7.8° to +8.3°) show that the L-configuration is complete and free of D-Rhamnose. In pharmaceutical synthesis, where stereochemistry directly affects therapeutic outcomes, this can't be changed.

Better reaction with Maillard

Because it is made up of deoxy sugar, it browns faster than regular hexoses without the help of enzymes. This means that companies that make flavours can use lower processing temperatures to make flavour combinations that are richer and more true to life.

Naturally derived from plants

It comes from Sophora japonica and is free of GMOs and allergens. To prove cross-contamination controls during milling, an allergen statement sheet can be sent upon request.

Product Specification

L-Rhamnose Monohydrate Application

1. Industrial Flavor Synthesis

Using controlled heat to react with amino acids like alanine or proline creates Furaneol, which is the molecule that gives real strawberry, caramel, and meat flavours. It is more efficient than glucose at Maillard reactions, which makes it the best precursor for making high-fidelity reaction flavours.

2. Dermo-Cosmetic Formulations

In high-end anti-aging skin care, it works on the Dermo-Epidermal Junction (DEJ), activating fibroblast receptors to increase the expression of Collagen IV and VII. This makes the skin's structure stronger and reduces the depth of wrinkles in a way that no other sugar ingredient can match.

3. Pharmaceutical Chiral Synthesis

It is used as a starting point for L-nucleosides, heart glycosides, and complex macrolides because it is a chiral pool material. It can be used to make high-purity drug substances because it doesn't get racemised during the protection and deprotection steps in organic solvents.

OEM / ODM Support

As a customer, you can ask for specifics like changed purity levels, particle size ranges, and Packaging formats. Hongda works with powder, capsules, tablets, and powder that has already been mixed.

You can put your own logo on private-label packaging. During the consultation, minimum order numbers and lead times are made clear. There is one-on-one project help from the sample stage all the way through bulk production.

Why Choose Us?

A manufacturer that has been around since 2001 and has 20,000m² facilities that make 3,000 tonnes of goods every year.

Kosher, Halal, BRC, Organic (EU & NOP), ISO9001, ISO22000, cGMP, and FSSC22000 are some of the quality systems that have been approved.

SGS-approved in-house lab with third-party checks by SGS and Eurofins

Plant identification using Sophora japonica planting bases

Quick shipping: 3–7 business days with a 3,000⎡ warehouse and organised inventory management

Full paperwork: COA, allergen statements, natural origin reports, and optical rotation records for each batch are all provided.

Production Process

This deoxy sugar is taken out by Shaanxi Hongda using a controlled acid hydrolysis process on Rutin that comes from their own Sophora japonica plant sources. The steps of the process are clearly laid out:

Finding raw materials, breaking down rutin with acid, crystallisation, cleaning, drying, HPLC analysis, quality control check, and packaging.

With over 10 production lines and a workshop that cleans to a level of 100,000, batch quality is always the same. Before being released, each batch goes through physical testing (such as particle size and appearance), chemical testing (such as purity, LOD, and ash), heavy metal screening, and microbiological proof.

Product Package

Our Factory

Our Certifications

Our Exhibitions

Delivery Method

FAQ

Q1: What kind of plants do you use to make your product?

A: It is taken from Sophora japonica by breaking down Rutin or Quercetin with acid. This makes sure that it has a natural L-configuration and is not made from GMOs.

Q2: What is the difference between the form that is monohydrate and the form that is anhydrous?

A: It's the monohydrate. When anhydrous rhamnose takes water from the air, it changes back to monohydrate, which leads to caking. For estimates about synthesis, the ~10% water of crystallisation needs to be taken into account.

Q3: How do you know if something is pure?

A: HPLC tests the assay to 98.0%. Optical rotation between +7.8° and +8.3° shows chiral identity and the lack of D-isomer contamination.

Q4: How much space do you need?

A: Keep the monohydrate crystal structure safe by storing it in drums with tight lids and inner liners, away from moisture and temperatures above 40°C.

Q5: Is it good for use in pharmaceuticals?

A: USP/EP limits for heavy metals and arsenic are met. Each batch's optical clarity is checked. You can get pharmaceutical-grade paperwork, like a COA and reports from a third party, if you ask for it.

Q6: What kinds of changes can be made?

A: Hongda can make custom purity grades, particle sizes, and packaging forms. OEM and ODM services include powders, capsules, tablets, and ready-to-use mixtures, and private-label options are available.

Contact Us

Ready to source pharmaceutical-grade L-Rhamnose Monohydrate? Send your inquiry to duke@hongdaherb.com and our team will respond within 24 hours.