L Ergothioneine Powder

L Ergothioneine Powder — High-Purity Fermentation Grade Antioxidant for Anti-Aging & Neuroprotective Formulations

Shaanxi Hongda Phytochemistry Co., Ltd. is a L Ergothioneine Powder manufacturer and supplier with more than 20 years plant extract production experience. Produced in a 100,000-level clean room, it has 98% purity of fermentation-grade ergothioneine and is guaranteed by KOSHER, HALAL, ISO9001, ISO22000, BRC and ORGANIC Certifications. With an annual output capacity of 3,000 tons, an in-house SGS-standard laboratory and a dedicated professor-level R&D team, we deliver consistent batch quality and fast 3-7 working day lead times – giving you a reliable, traceable raw material source for premium supplement and cosmetic formulations.

Product Introduction

L Ergothioneine Powder (CAS No. 497-30-3) is a sulfur-containing amino acid derivative classified as a thiol/thione compound. It is biosynthesized naturally by specific fungi and mycobacteria, then refined through precision microbial fermentation to guarantee 100% L-isomer stereochemical purity.

What sets this ingredient apart is its dedicated human transporter protein, OCTN1 (SLC22A4). This transporter actively carries ergothioneine across cell membranes, allowing it to accumulate specifically in tissues under oxidative stress — including the liver, eyes, skin, and mitochondria.

Its body half-life is approximately 30 days, far longer than common antioxidants. This means one dose delivers sustained cellular protection without rapid metabolic clearance.

Product Specification

Third-Party Test Report

Every batch of our ergothioneine is tested before shipment. Testing follows both internal protocols and authorized third-party verification through SGS and Eurofins.

Tests performed on each batch include:

· Purity: HPLC analysis confirming ≥98% L-isomer content

· Heavy metals: Atomic absorption spectrophotometry

· Pesticide residues: GC / LC-MS screening

· Microbiological safety: Total plate count, yeast, mold, E. coli, Salmonella

· Moisture & physical parameters: Bulk density, particle size, appearance

Test reports are available upon request for every production batch.

L Ergothioneine Powder Advantages

1. Superior Stability in Formulations

Unlike Vitamin C, which degrades rapidly in aqueous solutions, ergothioneine maintains structural integrity across a pH range of 3.0–9.0 and temperatures up to 100°C. This makes it suitable for complex multi-phase cosmetic and nutraceutical formulations.

2. Targeted Cellular Delivery via OCTN1

No other common antioxidant has a dedicated human transporter. Ergothioneine actively enters cells and accumulates in high-oxidative-stress tissues — not just circulating in plasma.

3. No Auto-Oxidation

Its thione-thiol equilibrium prevents spontaneous oxidation in aqueous environments, a significant problem with glutathione-based formulations.

4. Long Half-Life

With a tissue half-life of approximately 30 days, a small active dose delivers prolonged protection — reducing the required concentration in finished products.

5. 100% L-Isomer Purity

Produced via microbial fermentation, the product contains only the bioactive L-form. The inactive D-isomer is absent, confirmed by specific optical rotation testing.

L Ergothioneine Powder Application

OEM / ODM Support

Shaanxi Hongda provides one-to-one customized product solutions for brands, formulators, and private label companies. You can request:

· Custom purity specifications (98% or 99%+)

· Custom particle size for specific formulation needs

· Blended premix powders combining ergothioneine with complementary actives

· Finished dose forms: capsules, tablets, soft gels, sachets

Packaging can be customized with your brand label. Minimum order quantities are flexible for sampling and scale-up. Your product can move from concept to market-ready formulation with our team's direct technical support.

Why Choose Us?

· Established manufacturer since 2001 — over 20 years of plant extract and amino acid production

· 20,000 m² production facility with 10+ modern production lines

· 3,000 tons annual output capacity — ready to scale with your demand

· In-house SGS laboratory with HPLC, GC, UV, AAS testing equipment

· 20+ professor-level R&D personnel for technical support and custom development

· Multi-certification portfolio: KOSHER, HALAL, BRC, ORGANIC (EU & NOP), ISO9001, ISO22000, cGMP, FSSC22000

· Fast delivery: 3–7 working days with 3,000 m² fully stocked warehouse

· Third-party verified: SGS and Eurofins test reports available per batch

Production Details

Production Process

Shaanxi Hongda produces ergothioneine through precision microbial fermentation biosynthesis. This approach guarantees stereochemical purity and avoids synthetic contamination issues.

The key production steps are:

1. Strain selection — Specific fungal or bacterial strains with natural ergothioneine biosynthesis pathways

2. Controlled fermentation — Temperature, pH, and nutrient parameters precisely managed

3. Extraction & isolation — Separation from fermentation broth under controlled conditions

4. Purification — Multiple chromatographic steps to reach ≥98% purity

5. Drying & milling — Spray or freeze-drying to achieve consistent white crystalline powder form

6. QC testing — Full COA testing before release

All production is carried out in a 100,000-level purification workshop with cGMP-compliant procedures.

Our Factory

Our Certifications

Our comprehensive certification portfolio reflects our commitment to quality greatness. We hold cGMP certification guaranteeing pharmaceutical-grade fabricating measures. FSSC22000 and ISO22000 certifications ensure nourishment security administration compliance.

HALAL and Legitimate certifications extend your showcase reach to assorted buyer portions. Our Natural certifications (EU and NOP) bolster clean-label item improvement. ISO9001 certification illustrates our orderly approach to quality management.

These certifications empower smooth showcase section over distinctive locales and administrative situations. Standard reviews keep up our certification status and ceaseless change culture.

COA (Certificate of Analysis)

Full COA documentation is provided with each shipment. Custom testing reports aligned with your regional regulatory requirements are available on request.

FAQ

Q1: What is the purity of your product?

A: Our normal specification is ≥98% via HPLC. Higher purity grades (≥99%) are available on request for specialised applications.

Q2: How is ergothioneine produced — synthetic or fermentation?

A: It's made by precision microbial fermentation biosynthesis. This guaranties 100% L-isomer content, safety and clean-label compliance – no synthetic chemical methods are utilised.

Q3: How stable is this chemical in water-based cosmetic products?

A: Yep. It is stable at pH 3.0–9.0 and temperatures up to 100°C and is hence suitable with most aqueous and heat-processed formulations.

Q4: What certifications does the product have?

A: Current certifications are KOSHER, HALAL, BRC, ORGANIC(EU and NOP), ISO9001, ISO22000 and cGMP. Copies of full certificates on application.

Q5: Do you send samples before making large order?

A: Yeah. Samples (20–100 g) are obtainable. For sample packaging, the product is protected during transit with a thickened PE inner bag and aluminium foil outer bag.

Q6: What is the MOQ and lead time?

A: Standard bulk orders are shipped in 25 kg drums (27 drums per pallet). 3-7 Business Days Delivery. Reach out to explore MOQ flexibility for new customers or development projects.

Contact Us

Ready to source high-purity ergothioneine for your next formulation with L Ergothioneine Powder? Send your inquiry to duke@hongdaherb.com and our team will respond within 24 hours.