Chitosan Hydrochloride Powder

Chitosan Hydrochloride Powder - Premium Water-Soluble Biopolymer

Shaanxi Hongda Phytochemistry Co., Ltd. is a leading producer and supplier of Chitosan Hydrochloride Powder with excellent quality, bringing you unparalleled benefits of product purity, stability and application adaptability. We supply direct from our factory, so you get the best prices without a middle man. We have over 20 years experience in production, sophisticated 100,000-level purification workshops and strict quality control systems. We provide the product with constant DAC 90% specification, which meet worldwide pharmaceutical and food grade standards. Our water-soluble formulation alleviates the critical pH limitation difficulty you have with typical chitosan products enabling easy integration into your neutral pH formulations without acidic pre-treatment. This means faster production cycles, lower processing costs and better end-product performance for your pharmaceutical, agricultural and cosmetic applications.

Product Introduction

Chitosan HCL powder is a breakthrough water-soluble cationic polysaccharide, produced by controlled hydrochlorination of deacetylated chitin. This premium biopolymer dissolves readily in water at neutral pH ranges eliminating the acid-dependency that limits typical chitosan usage. Shaanxi hongda phytochemistry's chitosan powder has an outstanding biocompatibility, biodegradability and cationic charge density with a degree of deacetylation of up to 90 %. The off-white powder displays excellent mucoadhesion and a broad spectrum of antibacterial action making it a suitable functional ingredient for high end applications where biological safety and technical performance are both required. Our manufacturing process delivers uniform molecular weight distribution and low levels of contaminants, providing you with reliable raw material for important formulations.

Third-Party Test Report

Microbiological Safety Verification: Independent SGS testing confirms our product maintains total plate count below 1,000 CFU/g, with yeast and mold under 100 CFU/g, meeting stringent pharmaceutical excipient requirements. E.coli and Salmonella tests are negative, hence safe for oral and topical treatments.

Heavy Metals Testing: Eurofins lab certification confirms conformity with international safety requirements; lead concentration is below 1.0 ppm, arsenic is below 1.0 ppm, cadmium is below 0.5 ppm, and mercury is below 0.1 ppm, meeting USP and EP pharmacopeial criteria.

Pesticide Residue Screening: Comprehensive multi-residue analysis screens for more than 500 pesticides, and detects none of the tested substances. This confirms our raw materials are from controlled agricultural bases and processed in a clean environment.

Solubility Performance Testing: Third party validation shows 98% dissolving rate in distilled water in 30 minutes at room temperature versus less than 10% with normal chitosan, showing greater water solubility that will simplify your formulation operations.

We can provide you chitosan series products as bolow specificaiton:

Please contact our professional team to get COA and more information:​​​​​​​duke@hongdaherb.com

Chitosan Hydrochloride Powder Advantages

Immediate Water Solubility: Our hydrochloride version dissolves fully in neutral water within minutes, unlike typical chitosan. This lets you streamline formulation processes and bypass pH adjustment steps that can destabilise delicate active ingredients.

Enhanced Cationic Activity: Featuring protonated amino groups throughout the polymer chain, this material displays a greater positive charge density compared to standard chitosan, offering you with increased antimicrobial efficacy against Gram-positive and Gram-negative bacteria, along with superior binding capacity to negatively charged biological surfaces.

Excellent Biocompatibility: Toxicology tests indicate non-cytotoxic profiles across many cell lines giving you confidence in creating treatments for oral, topical and injectable routes without the safety issues characteristic of synthetic polymers.

Superior Film-Forming Properties: The material creates transparent, flexible films with excellent oxygen barrier characteristics, enabling you to develop advanced wound dressings, edible coatings, and controlled-release matrices with predictable mechanical properties.

Stable Supply Chain: Vertically integrated production from chitin extraction to final powder, gives you consistent quality batch-to-batch. Certificates including HALAL, KOSHER, BRC, ISO22000 and cGMP enabling your global market access requirements.

Chitosan Hydrochloride Powder Application

Pharmaceutical Drug Delivery Systems: This polymer can be used in the formulation of nanoparticles and microspheres for encapsulation of peptide medicines, proteins and vaccines. The water solubility enables encapsulation without the use of harsh chemical solvents or denaturing acids, thereby retaining the biological activity and improving the intestinal permeability via paracellular transport mechanisms, resulting in improved bioavailability of poorly absorbed medicines.

Agricultural Biostimulant Solutions: Can be used as a seed coating or foliar spray to stimulate the innate immunity of the plant by chitinase production and defensive metabolite creation. Unlike conventional chitosan that precipitates in hard water, our direct water solubility guarantees consistent coverage and efficacy over a range of soil pH and water hardness conditions, providing you with guaranteed disease prevention and stress tolerance enhancement.

Advanced Wound Care Products: Cationic polymer quickly attracts red blood cells in haemostatic dressings and healing bandages to speed blood clotting and establish an antibacterial barrier by electrostatically binding with the bacterial cell membranes. This double functionality will cut infection and healing time and will provide you competitive advantages on medical device markets.

Improvement of Cosmetic Formulation: It is a hair conditioning chemical that binds to anionic sites on damaged hair shafts, hence smoothing cuticles and enhancing manageability. In skincare it is a moisturising film-former that does not need neutralisation in the production process, making your manufacturing process easier, while offering consumers noticeable benefits in texture and moisture.

Production Process

Step 1 - Raw Material Selection: We purchase high-quality chitin from controlled crustacean shell supply and execute thorough incoming inspection for protein content, moisture levels and contaminants. This results in baseline purity levels above 95% and provides the basis for outstanding final product properties.

Step 2 - Deacetylation Reaction: Chitin is subjected to controlled alkaline treatment in temperature controlled reactors where acetyl groups are sequentially eliminated. The goal degree of deacetylation of 90% is achieved with adequate control of reaction duration, temperature and alkali concentration and gives chitosan of appropriate cationic charge density.

Step 3 - Hydrochlorination: Deacetylated chitosan is reacted with hydrochloric acid in specified stoichiometric ratios to transform the amino groups into water-soluble hydrochloride salts. This important phase dictates the final solubility performance and requires professional process management to prevent over-acidification or incomplete conversion.

Step 4 - Purification and Washing: Multiple washing cycles with deionized water remove residual salts, proteins, and reaction byproducts. It is then centrifuged and filtered to reduce the ash concentration to below 1%. It is then treated to chelate heavy metals to meet purity standards for pharmaceutical grade.

Step 5 - Drying and Milling: Vacuum drying at carefully controlled temperatures is employed to maintain polymer integrity to moisture contents of less than 10%. Jet milling results in consistent 80 mesh powder with good flowability. Nitrogen purging during Packaging minimises oxidative degradation during storage and shipment.

OEM / ODM Support

Formulation Development Services: Work with our team of more than 20 experienced R&D experts to design custom formulations for incorporating Chitosan Hydrochloride Powder into your specific applications. If you require different viscosity classes, specific molecular weight ranges or blended compositions, we may modify the processing settings to suit your technical requirements.

Custom Packaging Solutions:  We offer variable packaging options from 1kg aluminium bags for sampling to bulk 500kg containers for industrial use, in addition to the typical 25kg barrels. Private labelling in your specifications with customised COA forms and regulatory documentation to speed your way to market.

Regulatory Documentation Support:  Our quality assurance team can take the load off your administration by providing you with complete technical dossiers such as DMF (Drug Master File) preparation support, allergen statements, GMO free declarations and region specific compliance paperwork for FDA, EMA and other regulatory submissions.

Technical Training and Application Guidance: Training on-site or virtually on best dissolve techniques, formulation troubleshooting and application specific best practices to ensure your technical team gets the greatest performance from your product in the shortest development period.

Why Choose Us?

You are satisfied with our 23 years history as professional phytochemical company with three professional planting bases to guarantee the traceable quality of raw material. Our factory is on a 20,000 square meters area with more than 10 manufacturing lines, and 100,000 level purification workshops. Annual production capacity is more than 3,000 tonnes to ensure the stability of supply for your rising needs. A full quality verification by HPLC, GC and ICP-MS instruments is done in an SGS-standardized laboratory run by university professors. Further third party validation is done by collaborative efforts with Eurofins.

Your orders receive special attention by professional account managers who collaborate with our technical, quality and logistical teams to deliver on time within 3-7 working days. Our Certifications include cGMP, FSSC22000, ORGANIC (EU/NOP) and numerous patents for our processing innovations, so you have a trusted partner that can support your current production needs and future product development initiatives across pharmaceutical, agricultural and cosmetic sectors.

FAQ

Q: What’s special about your product compared to regular chitosan?

A: Our product dissolves immediately in neutral pH water, without the need for acidic solvents, avoiding formulation complexity and permitting usage in pH sensitive applications where standard chitosan fails.

Q: Can you offer samples for testing?

A: Yes, we can send 50-100g samples in aluminium foil packing for your evaluation. It will be shipped out within 3-5 working days by international courier, for your testing to see if it is suitable for your formulations.

Q: What is the minimum order quantity?

A: Our typical MOQ is 100kg (4 drums) however we are able to take lesser initial orders for new customers to help your product development and keep the cost down.

Q: Do you offer technical support on formulation development?

A: Yes, you are. Our R&D team offers full technical consulting services including dissolution optimisation, compatibility testing help, and application-specific recommendations throughout your development process.

Q: How do you maintain consistent quality throughout batches?

A: Each production batch is subjected to 18-point quality verification including degree of deacetylation, solubility performance and microbiological testing. Full traceability documentation is maintained and retention samples are kept for three years.

Verified purchase

1. I’ve been using Nutricology Shaanxi hongda 's Chitosa powder for a few weeks now, and I’m genuinely impressed with the results. The quality of this product is outstanding — it’s easy to take, gentle on the stomach, and I’ve noticed a significant improvement in my overall well-being. I also value Shaanxi hongda’s commitment to purity and science-based formulas.

2.I’m really impressed with Shaanxi hongda's Chitosan hcl powder. The quality is outstanding, and it supports immune health, detoxification, and cellular protection. I feel more balanced and energized since adding it to my routine. The capsules are easy to take, and the formula feels very clean. It’s a unique and powerful supplement with noticeable benefits. Definitely a hidden gem in my health toolkit.

Contact Us

Ready to enhance your formulations with premium Chitosan Hydrochloride Powder? Contact Us today at duke@hongdaherb.com to request samples, obtain quotations, or schedule a technical consultation with our specialists.