Is Melatonin The Magic Cure For Insomnia

Does Melatonin Really Help You Sleep?
For the question that everyone is concerned about: how to effectively help sleep? Does pure melatonin powder really work? First of all, through relevant statistical investigations, bulk melatonin powder can be determined that melatonin powder is closely related to sleep and light: with increasing age, melatonin in the human body shows a downward trend, which means that the phenomenon reflected is: the elderly sleep for a long time Short time, insomnia and even rapid aging. According to statistics, young people who play with mobile phones or tablets for more than two hours before going to bed every night will have 22% less melatonin in their bodies than others, because the stimulation of light (blue light) will be transmitted to our eyes through our eyes. The pineal gland of the brain inhibits the secretion of melatonin, which in turn leads to the secretion of hormones, which stimulate the nerves of the brain and make people excited. Taking quantitative melatonin can significantly improve their melatonin levels, increase sleep quality, and alleviate and treat insomnia to a certain extent. Therefore, melatonin is helpful to sleep.

Is melatonin the magic cure for insomnia?
Melatonin protein powder is isolated from the pineal gland, a bean-sized tissue that attaches to the back wall of the third ventricle in humans, to discolor the frog's skin. The effect of melatonin in amphibians is antagonistic to that of melatonin, which can promote skin depigmentation, but the skin color of mammals does not respond to melatonin.
In the 1970s, studies found that the production of melatonin is related to the body's circadian rhythm. As the biological clock of the human endocrine system, melatonin has the functions of regulating the endocrine system, maintaining the stability of the body's internal environment, enhancing immunity, and delaying aging. Its most notable function is to regulate sleep. So, is melatonin really effective?

Melatonin is mainly an amine hormone produced by the pineal gland in the human brain and mammals. The content of melatonin bulk powder in the human body is extremely low, and the secretion cycle is more white than black. This diurnal secretion cycle of the brain sends a "time signal" to the central nervous system, which induces drowsiness.
In recent years, many products have been advertised to help sleep, but are those exogenous melatonin really effective in helping sleep? Can melatonin supplementation really help with insomnia? Through the comparison of comprehensive experimental studies,calm melatonin powder can be basically confirmed that for patients with primary insomnia, melatonin cannot improve the efficiency of sleep, but it can shorten the time to fall asleep. That is to say, exogenous supplementation of melatonin mainly improved the difficulty of falling asleep, but did not improve the overall sleep quality and sleep efficiency.
Another effect of melatonin is to improve jet lag sleep, such as jet lag and sleep improvement in shift work. The results of the study show that the effectiveness of melatonin in relieving jet lag does not alleviate sleep disturbances, but it can improve jet lag. Problems with daytime fatigue.
Fundamentally speaking, melatonin powder is different from sleeping pills. Pure melatonin powder mainly regulates sleep by regulating the circadian rhythm of the brain, reduces sleep latency and reduces light exposure at night, and promotes endogenous melatonin rhythm. phase advance and reset of the endogenous clock. It is found that melatonin has an effect on the sleep time of patients with primary sleep disorders but does not affect the sleep effect, and will not cause potential harm to the body like sleeping pills.

In terms of safety, pure melatonin is an endogenous physiological substance, and it is safe to use exogenous melatonin in a short period of time, such as a few days or weeks. All formulations are also safe. However, long-term results are unknown.

Three physiological characteristics of melatonin:
1. Melatonin is affected by light and exhibits diurnal secretion regularity. The concentration of melatonin in the blood is the lowest at 8:00 in the morning, and it begins to be secreted at around 20:00 in the evening. It gradually increases with time, and at 23:00 at night After that, it rises rapidly, reaches the peak at 2-3 in the morning, and then gradually declines, and the sleep gradually becomes shallower, until it wakes up naturally in the morning. Therefore, the first physiological characteristic of melatonin is that its secretion is regular, which is a natural sleep biological clock regulator, which automatically tells us that we are about to enter sleep time;
2. The secretion of melatonin is related to age. After the age of 35, the gland function of the human body decreases, and the secretion of melatonin decreases, with an average decrease of 10% to 15% every 10 years. Therefore, the decline of melatonin in the elderly is the most obvious. Obvious, leading to sleep rhythm and multiple system dysfunction;
3. The secretion of melatonin is also affected by light. The secretion of melatonin increases at night, but as long as there is visible light, the secretion of melatonin will be inhibited. Therefore, getting up frequently at night and having light will obviously affect melatonin. The secretion of hormones can lead to difficulty in falling asleep and the decline in sleep quality.

What does melatonin do to the body？
1. Melatonin can delay aging
Melatonin sleep powder can scavenge free radicals, inhibit lipid peroxidation, protect cell structure from DNA damage, and reduce peroxide levels in the body. Studies have shown that the protection rate of melatonin to safrole (a carcinogen that damages DNA by releasing free radicals) reaches 99%. With obvious antagonistic effect, it can also reduce the content of LPO in the brain, acting on the epidermis, cerebellum, hippocampus, hypothalamus, striatum and other tissues of the brain;
2. Melatonin may be anti-tumor
Research experiments have shown that melatonin has a protective effect on the mutagenicity caused by Zilimycin C, can reduce the formation of DNA synthesis induced by chemical carcinogens (safrole), and prevent DNA damage. Melatonin can also inhibit tumor growth in tumor-bearing mice and prolong the survival time of mice. At the same time, melatonin supplements have a certain effect on female breast cancer, and can promote endogenous granulocytes and leukocytes through bone marrow T-cells. Macrophages, which promote the production of accumulation factors, serve as adjuvant drugs for tumor diseases;
3. Melatonin can improve sleep
Pure melatonin powder can significantly regulate the serum concentration in the brain, improve sleep time, shorten the time to fall asleep, reduce the number of sleep awakenings, deepen sleep, etc., reduce hormone secretion, improve insomnia, dreaminess, difficulty falling asleep, jet lag insomnia and other problems;
4. Melatonin Can Help Regulate Immunity
Melatonin protects against paralysis and death resulting from acute stress caused by infectious agents (sublethal doses of cerebral myocardium virus). Enhance the activity of NK and LAK in spleen cells, promote the induction of IL-2, enhance the phagocytosis of cells, activate human monocytes, induce cytotoxicity and regulate the function of IL-1 secretion.

What are the uses of melatonin?
1. Medical field
Melatonin powder has long been used in the medical field for the treatment of sleep disorders, insomnia, etc., as well as pharmaceutical agents for anti-cancer and liver diseases;
2. Field of health preservation
In the field of health preservation, melatonin can help improve the immune function of the human body, reduce the risk of people suffering from cancer, heart disease and other diseases, and help everyone maintain a healthy body;
3. Beauty field
Wwholesale melatonin powder is very popular in the beauty industry. It can not only promote skin metabolism, reduce skin aging, help skin regeneration, but also prevent pigmentation, enhance skin elasticity, and delay skin aging.

How much melatonin is the most appropriate?
Generally speaking, taking melatonin is safe as long as it is not excessive, and there are few adverse reactions. The best melatonin content in the human body is about 0.1-0.3mg. It is safe for patients with sleep disorders to take melatonin continuously for 3 months at a dose of about 3-30mg. Our tests have proved that melatonin has no obvious harm to liver and kidney function, blood circulation, and urinary tract, indicating that taking small doses of melatonin in a short period of time is safe and has no obvious side effects.
There are a small number of adverse reactions in clinical studies, such as daytime drowsiness, headache, nausea and fatigue. Excessive use of melatonin can easily lead to poor mental state, drowsiness, fatigue, distraction, decreased responsiveness and sensitivity. Therefore, it should be taken with caution when driving, mechanically operating or engaging in dangerous operations. In addition, the effect of melatonin on children and pregnant women is not yet clear, and some literature shows that high-dose melatonin can affect ovulation and increase the difficulty of pregnancy.

How to choose melatonin powder?
1. Melatonin powder belongs to the health care category, and you need to choose a regular manufacturer when purchasing (Shaanxi Hongda has specialized in the production and export of melatonin for 20 years and has obtained cGMP qualification certification);
2. Melatonin is generally very effective for the elderly over 55 years old and people with sleep disorder (jet lag, night shift, on duty). For other types of sleep disorders, it is recommended to consult a doctor;
3. Pay attention to the choice of dosage form. Ordinary melatonin preparations are not effective in promoting sleep in a short period of time, while melatonin sustained-release preparations can treat insomnia indications, and can relieve various sleep disorders when used for insomnia patients older than 55 years old.