Diosgenin Extract
2.Appearance: Off-White Powder
3.Specification: 98% Diosgenin
4.CAS NO: 512-04-9
5.Packing Specification: 25kg/drum, 27 drums/tray
6.Delivery: 3-7working days
7.Main Market: European, North America, Asia
8.Certification: KOSHER,HALAL,BRC,ORGANIC,ISO9001,ISO22000 etc.
Premium Diosgenin Extract 98% HPLC - Professional Phytosteroid Solution from Certified Manufacturer
Shaanxi Hongda Phytochemistry stands as a leading manufacturer and supplier of high-purity Diosgenin Extract, delivering pharmaceutical-grade solutions to global markets since 2001. By using our modern extraction technique and 100,000-level purification processes, we are able to create product with remarkable purity levels approaching 98% by HPLC, from premium Dioscorea zingiberensis tubers. We have HALAL, KOSHER, cGMP, FSSC22000, and ISO22000 Certifications and produce 3000 tonnes annually. We provide dependable pharmaceutical intermediates for steroid hormone synthesis and nutraceuticals to reduce manufacturing costs and ensure quality.
Diosgenin Supplier
Our diosgenin powder is a crucial bioactive phytosteroid sapogenin, produced from Wild Yam tubers with a regulated hydrolysis of acid. This off-white crystalline powder is the classic starting material for semi-synthesis of more than 60% of the commercial steroidal medicines in the world. 98% Diosgenin has a sharp melting point of 204-208°C and specific rotation of -129° to -135° indicating a strong chiral purity. Its lipophilic nature provides great solubility in organic solvents and is thus suitable for pharmaceutical processing and formulation development.
Diosgenin Extract Advantages
Pharma-Grade Purity Our minimum 98% test ensures great stoichiometric efficiency in the Marker Degradation pathway, reducing steroid synthesis side-reaction byproducts.
Stable Supply Chain: Our plant-derived sterols resist animal-sourced instability and save downstream purification costs.
Enhanced physicochemical characteristics: The uniform aglycone structure allows manufacturers to sidestep intricate complete synthesis pathways, thereby ensuring steady manufacturing prices of identical-to-nature hormones.
Rigorous Quality Control: Each batch is tested for residual solvents and meets ICH Q3C criteria for ethanol, petroleum ether, and acid residues.
Our Diosgenin is refined using low-temperature crystallization and dual-vacuum drying, ensuring organic solvent residues (Ethanol/Hexane) are well below EP/USP strict limits (Residual Ethanol < 500 ppm). The final powder is odorless and ultra-pure.
Diosgenin Specification
30 years OEM Product manufacturer
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Items
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Standards
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Results
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Physical Analysis
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Appearance
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Fine Powder
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Conforms
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Color
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White Powder
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Conforms
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Odor
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Characteristic
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Conforms
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Mesh Size
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100% through 80 mesh size
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Conforms
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General Analysis
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Identification
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Identical to R.S. sample
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Conforms
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Diosgenin
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≥98%
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98.8%
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Extract Solvents
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Water and Ethanol
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Conforms
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Loss on Drying (g/100g)
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≤5.0
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3.24%
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Ash(g/100g)
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≤5.0
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2.05%
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Chemical Analysis
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Pesticides Residue (mg/kg)
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0.05
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Conforms
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Residual Solvent
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<0.05%
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Conforms
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Residual Radiation
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Negative
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Conforms
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Lead(Pb) (mg/kg)
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<3.0
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Conforms
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Arsenic(As) (mg/kg)
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<2.0
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Conforms
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Cadmium(Cd) (mg/kg)
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<1.0
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Conforms
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Mercury(Hg) (mg/kg)
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<0.1
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Conforms
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Microbiological Analysis
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Total Plate Count(cfu/g)
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≤1,000
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300
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Molds and Yeast (cfu/g)
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≤100
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29
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Coliforms (cfu/g)
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Negative
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Conforms
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Salmonella(/25g)
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Negative
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Confor
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Why Choose Us?
Shaanxi Hongda has 20,000 square meters of state-of-the-art facilities and more than two decades extraction experience. Our patent technology and national high-tech firm status indicate our dedication to innovation. You will like our professor-led R&D team, systematic quality management based on cGMP and FSSC22000 standards, varied 3000-square-meter warehouses guaranteeing rapid delivery within 3-7 working days. With a wide range of certifications we can help you break into European, North American and Asian markets and our low price structure supports your profitability.
Diosgenin Extract Applications
Pharmaceutical Intermediate Production: Main raw material for 16-DPA (16-Dehydropregnenolone Acetate), the intermediate for testosterone, oestradiol, dexamethasone, and spironolactone.
Functional Dermocosmetics: It suppresses melanogenesis, promotes keratinocyte proliferation, and forms collagen in anti-aging treatments without changing hormones.
In menopausal and metabolic health supplements, nutraceuticals compete with cholesterol absorption and promote biliary excretion to decrease cholesterol.
Manufacturing Process
Step 1: High-quality Dioscorea zingiberensis tubers are selected by agronomists from our approved planting bases to assure a high supply of Diosgenin Extract.
Step 2: Acid Hydrolysis Extraction: Controlled acid treatment breaks down the glycosidic connections in dioscin saponins, liberating free diosgenin aglycone with little heat degradation.
Step 3: Purification and Crystallisation: Our 100,000 level purification workshop eliminates contaminants by multi-stage solvent extraction and recrystallisation to pharmaceutical-grade purity.
Step 4: Quality Testing and Packaging: SGS laboratory analysis verifies HPLC purity, heavy metal concentration, and microbiological safety before aseptically packing in double-layer PE bags in fibre drums.
Third Party Test Report
Analytical Verification: Our goods are tested by globally accredited labs (SGS, Eurofins…) guaranteeing traceability and compliance.
HPLC Analysis: The presence of Diosgenin is confirmed by state of the art high-performance liquid chromatography. Minimum purity: 98.0% (effectively removes yamogenin isomers and structural analogues).
Pesticide Residue Testing: Full screening for accordance with EU and FDA regulations, all substances tested are below detection limits.
Heavy Metal Analysis: ICP-MS testing confirms Lead <2ppm, Arsenic <2ppm and total heavy metals <10ppm in accordance with ICH Q3D recommendations for pharmaceutical uses.
OEM/ODM Service
Custom Formulation Development – Work with our 20+ PhD R&D team to design custom specs to fit your particular pharmaceutical or nutraceutical needs.
Flexible Packaging Solutions: We provide customised packaging solutions from 100g samples to 25kg bulk containers and private labelling choices to suit your branding demands.
Regulatory Documentation Assistance: Full paperwork including COA, allergy declarations, BSE/TSE certifications and stability data is available to assist your product registration procedures.
Large Scale manufacturing Capacity 10 manufacturing lines with an annual capacity of 3000 tonnes provide a steady supply of trial batches and commercial orders in large quantities.
Customer Reviews:
“We use diosgenin as a key precursor in our synthesis process. With previous suppliers, batch quality was highly inconsistent—sometimes the powder had a yellowish-brown tint, which directly impacted the final product yield. Hongda’s 98% diosgenin is exceptionally white and free of any residual organic solvent odor. The HPLC chromatograms provided with the shipment align perfectly with our internal verification results, saving us a great deal of time and hassle regarding re-testing.” — Dr. Stefan M., Senior QC & Procurement Lead, Germany
“Our facility uses diosgenin for capsule filling; the biggest challenges with plant-based raw materials are static electricity and clumping due to moisture absorption. Hongda’s diosgenin excels in bulk density and particle size control; it flows freely through the hopper without sticking to the walls or punches. Since switching to their material, our capsule production line has seen a nearly 20% increase in daily output.” — Jason K., Operations Manager, USA
FAQ
Q: What is the minimum order quantity?
A: Our MOQ is 25kg per order, however sample 100-500g are available for quality assessment.
Q: Do you have organic certification?
A: Yes, we have both EU and NOP organic certification for clients that need certified organic goods.
Q: How long will it last if stored correctly?
A: When kept in sealed containers at room temperature, away from light and moisture, our product is stable for 24 months.
Q: Do you provide bespoke purity specifications?
A: Definitely. Our R&D expertise enable us to tailor purity levels from 95% to 98%+ according on your application needs.
Ready to secure your pharmaceutical-grade Diosgenin Extract supply? Contact our technical team at duke@hongdaherb.com for detailed specifications, competitive quotations, and customized solutions tailored to your production needs.
