Gmp Levamisole Powder Supplier

Levamisole HCl powder is the L-body of tetramisole, which can selectively inhibit the succinate dehydrogenase in the muscle of the worm, so that the fumaric acid cannot be reduced to succinic acid, thereby affecting the anaerobic metabolism of the muscle of the worm and reducing energy production.
When the parasite comes into contact with it, it can depolarize the neuromuscular, and the muscle continues to contract to cause paralysis; the cholinergic effect of the drug is conducive to the excretion of the parasite. Its activity is about 1 to 2 times that of tetramisole (racemate), and its toxicity and side effects are low. Drugs may have an inhibitory effect on the microtubule structure of the parasite. Levamisole also has immune regulation and immune stimulation functions.

Levamisole hcl

COA

Test	Specification	Result	Remarks

Description

White or almost white, crystalline powder

Conforms

Visual inspection

Identification

(1) IR: Match with standard spectrum (2) HPLC

Conforms

By IR and HPLC analysis

Assay (Levamisole HCl)

98.0% - 102.0%

100.2%

By HPLC

Loss on Drying

≤ 0.5%

0.2%

105°C for 2 hours

4.5 - 5.5

5.2

pH of 1% solution

Heavy Metals

≤ 20 ppm

<20 ppm

By AAS or ICP analysis

Related Substances

Individual Impurity ≤ 0.5%

0.2%

By HPLC

Sulphated Ash

≤ 0.1%

0.05%

Ignition at 800°C

Residual Solvents

Methanol ≤ 3000 ppm, Acetone ≤ 500 ppm

Conforms

By GC

Microbial Limits

Total aerobic count ≤ 1000 CFU/g

300 CFU/g

Plate count method

Total Coliforms

Negative

Standard plate count method

E. coli

Negative

USP method

Endotoxins

≤ 0.5 EU/mg

0.2 EU/mg

Limulus amebocyte lysate assay

Levamisole Hydrochloride Benefits

Pharmacokinetics

Levamisole HCl powder is rapidly absorbed after oral administration, and within 2 hours after taking 6 tablets, the plasma concentration reaches the peak value (500mg/mL), and t1/2 is 4 hours. Metabolized in the liver, this product and its metabolites can be excreted from urine (mostly), feces and respiratory tract, and can also be detected in milk.

Indications

Our high-purity Levamisole hydrochloride soluble powder has a good curative effect in the treatment of roundworms, hookworms, pinworms, and strongyloidiasis. Due to the high efficiency of a single dose of this product, our GMP-compliant levamisole powder for poultry is ideally suited for group therapy. Compared with diethylcarbamazine, it has higher activity against adult worms and microfilariae of bancroftiana, malayia and onchocerca, but the long-term efficacy is poorer.

Levamisole Hydrochloride Benefits

Levamisole Hcl Dosage

Reliable Sourcing, Consistent Quality

Levamisole hcl powder

1. Adults should take 3/5 to 1 tablet/10kg of ascaris repellant orally, and children should take 1 tablet/10kg of levamisole hydrochloride powder before bed or on an empty stomach.
2. To fight hookworms, take 3/5~1 tablet/10 kg orally once a night for three days in a row.
3. To treat filariasis, take 1-2 pills per 10 kg twice or three times over the course of three days.

Levamisole Hcl Dosage

Medicine Interactions

Expertly Sourced & Supported

1. It can be used in conjunction with pyrantel to treat severe hookworm infections and enhance the effectiveness of repelling American hookworm.
2. Intestinal nematode mixed infection can be treated in combination with thiabendazole.
3. Filarial infections can be treated by using diethylcarbamate citrate sequentially.
4. To avoid making tetrachlorethylene more harmful, our premium levamisole powder should not be used with it.

From Synthesis to Supply: Our Quality-Focused Process

1. Controlled Synthesis: Manufactured in cGMP facilities using precise, standardized chemical processes.

2. Solvent-Free Refinement: Advanced purification techniques ensure high-purity pharmaceutical-grade material without residual solvents.

3. Triple Testing: Rigorous QC at raw material, in-process, and final batch stages against international pharmacopoeia standards.

4. Global Logistics: Flexible shipping options (EXW/FOB/CIF) via air or sea, with full regulatory documentation support.

Custom Solutions for Your Formulation Needs

Whether developing anti-parasitic boluses or medicated feed premixes, we adapt to your needs:

1. Concentration Adjustments: For premixes and oral solutions, with purity grades from 98% to 99.5%.

2. Blend Development: Custom formulations with carriers like calcium carbonate or rice hull powder for optimal mixing and stability.

3. Regulatory & Stability Support: Comprehensive stability data packages and documentation for global veterinary and pharmaceutical submissions.

4. Scalable Supply: Competitive MOQ with volume-based pricing to suit your production scale.

Where To Buy Levamisole Powder

We are always at your service when you need

Shaanxi Hongda was established in 2001. We are a manufacturer specializing in raw materials for veterinary drugs for animals and poultry. We mainly produces florfenicol, amoxicillin, enrofloxacin, metronidazole, abamectin, and tilmicol. Xing and other veterinary drug powders, premixes, granules, etc. are produced in strict accordance with international veterinary drug raw material standards, and all qualification Certifications are complete. Welcome to cooperate with us!

280

Time members

25+

years experience

15+

Certifications

Workshop Production Line