Troxerutin Powder

Premium Troxerutin Powder | High-Purity Vascular Health Ingredient for Pharmaceutical & Nutraceutical Applications

Shaanxi Hongda Phytochemistry Co., Ltd. stands as a leading manufacturer and supplier of premium-grade Troxerutin Powder, delivering 95% high-purity semi-synthetic bioflavonoid derived from Sophora japonica. 20 years'experience in botanical extraction, 20000 square meters manufacturing base, 10 contemporary production lines, 100000 level purification workshops, and the annual output capacity of 3000 tonnes. Our product is designed to overcome crucial formulation issues, offering greater water solubility and bioavailability compared to natural rutin, making it ideal for pharmaceutical-grade venous health treatments. We are certified with FSSC22000, cGMP, HALAL, KOSHER and ISO22000. You may be assured of the whole supply chain dependability from raw material planting in our specialised Sophora japonica planting site to delivery of completed products within 3-7 working days.

Troxerutin Factory

Sophora japonica extract troxerutin is a professionally designed extract of Sophora japonica buds, a vasoprotective substance, prepared using sophisticated hydroxyethylation methods. It is a yellow crystalline powder that contains 95% trihydroxyethylrutoside and has good water solubility, which cannot be achieved by natural flavonoids. The chemical is a strong phlebotonic, lowering capillary permeability, stiffening the walls of the vessels and improving microcirculation. Our troxerutin extract is manufactured according to the requirements of the European Pharmacopoeia EP 10.0 and guarantees pharmaceutical makers a constant quality for the treatment of chronic venous insufficiency, haemorrhoids and capillary fragility diseases.

Third Test Report

Testing Authority We partner with leading third-party labs globally, including SGS and Eurofins, to verify product quality and safety compliance.

Pesticide residual Analysis: Each batch is tested thoroughly for over 500 pesticide chemicals and meets the requirements of EU Regulation 396/2005 and FDA tolerance standards, with maximum residual limits substantially below detectable levels.

Heavy Metal Testing: All testing is done under stringent conditions, verifying lead <0.5ppm, arsenic <0.5ppm, mercury <0.1ppm, and cadmium <0.5ppm. All of which are pharmaceutical-grade safety criteria.

Microbiological Safety: Total plate count <1000cfu/g, yeast and mould <100cfu/g and absence of E.coli, Salmonella or Staphylococcus aureus, as per confirmed testing methodologies.

Product Specification

Troxerutin Powder Advantages

Enhanced Bioavailability: Modified molecular architecture leads to 3-5 times higher absorption than regular rutin extracts, permitting reduced effective doses in formulations.

Very Good Solubility: High solubility in water and glycerol allows wide use in transparent gels, injectable solutions and oral liquid formulations without stability problems.

Pharmaceutical-Grade Purity: Uniform 95% assay content and a rigorously maintained tri-hydroxyethylrutoside ratio assure consistent therapeutic results from batch to batch.

Multi-Functional Activity: Combines vasoprotective, anti-inflammatory and antioxidant activities in one compound, decreasing formulation complexity for producers.

Regulatory Compliance: Full documentation for drug master file submissions. EP, USP and ChP pharmacopoeia standards compliance.

Troxerutin Powder Usage

Pharmaceutical Manufacturing: Key Active Pharmaceutical Ingredient (API) for drugs treating chronic venous insufficiency, haemorrhoids, capillary stabilisation. Available in tablets, capsules and injectables.

Nutraceutical Products: A functional ingredient for vascular health supplements to aid leg oedema, varicose veins and circulation, possessing clinical effectiveness.

Dermocosmetic Formulations: An active ingredient in anti-aging creams and serums, it has anti-inflammatory properties, reduces redness and protects against blue light radiation damage.

Ophthalmic Solutions: Troxerutin Powder is a unique component in eye drops that targets capillary fragility and alleviates ocular inflammation via enhanced microcirculation.

Manufacturing Process

Step 1 – Selecting the Raw Material: High-quality Sophora japonica buds are picked from our certified organic planting base and are tested by HPLC to confirm the high content material of rutin before processing.

Step 2 – Rutin extraction: The plant material is subjected to controlled aqueous-ethanol extraction at optimised temperature and pH conditions, yielding a concentrated rutin extract with >95% purity.

Step 3 - Hydroxyethylation Reaction: Purified rutin reacts with ethylene oxide under precisely controlled alkaline conditions and temperature parameters, converting rutin into trihydroxyethylrutoside with superior solubility characteristics.

Step 4 - Purification and Crystallisation: The reaction mixture is subjected to multi-step chromatographic purification and then controlled crystallisation to produce pharmaceutical quality crystals with not less than 95% assay.

Step 5 - Quality Control and Packaging The finished product is subjected to a series of rigorous tests, including HPLC assay, heavy metals, microbiology, pesticide residues, and so on, and then packaged in double layer PE bags within fibre drums, under regulated humidity conditions.

Support OEM / ODM

Custom Specification Development Our R&D team develops custom specifications to meet your target market needs, such as specified test ranges, particle sizes, and excipient combinations.

Private Label Manufacturing: Full cycle branding services including label design, packaging and branding with your business name, including all regulatory documents and Certifications required.

Formulation Development: Technical knowledge in the development of stable formulations for tablets, capsules, soft gels and liquid medications with optimised bioavailability and shelf life.

Flexible MOQ: Ranging from 100kg for market testing, to multi-ton contracts for established items, with attractive price structures.

Comprehensive Documentation: Full Certificate of Analysis, MSDS, Allergen declarations, BSE/TSE certificates and stability data to meet your product registration needs.

Why Choose Us

Shaanxi Hongda Phytochemistry is a manufacturer of unrivalled dependability, with vertically integrated production that controls each and every step from cultivation to final product. A laboratory standardised to SGS and manned by 20+ PhD-level experts guarantees all batches to be consistent with pharmaceutical-grade quality. With over 23 years of botanical extraction expertise, we have strategically located raw material stockpiles to ensure on-time delivery even in the face of supply chain interruptions.

We have many international certifications including cGMP, FSSC22000 and ORGANIC (EU/NOP) that guarantee no regulatory hurdles to worldwide market access. Cooperating with Hongda means cooperating with a national high-tech firm that has independent extraction patents and 3,000 square meters of inventory warehouses to ensure the supply of goods.

FAQ

Q: What is the minimum order quantity for the product?

A: Our usual MOQ is 25kg (one drum), however we can provide lesser amounts for initial testing with sample packets ranging from 100g to 1kg.

Q: How do you ensure consistent quality across different production batches?

A: Each batch is fully tested with HPLC assay verification with full COA documentation. Our quality system includes standards for validating processes and tracing raw materials.

Q: What is the shelf life and storage condition?

A: The product is stable for 24 months when kept in sealed containers below 25°C, dry and shielded from light. We suggest the storing in a refrigerator for longer preservation.

Q: Can you provide regulatory support for product registration?

A: Yes, we do provide full documentation including drug master files, stability studies, manufacturing process descriptions and analytical techniques supporting FDA, EMA and other regulatory filings.

Q: Do you provide bespoke formulation development?

A: Sure thing. Our R&D team offers complete formulation development, stability testing, and scale-up assistance for pharmaceutical and nutraceutical applications.

Contact Us

Ready to source premium Troxerutin Powder for your formulations? Email us at duke@hongdaherb.com  and discover how Shaanxi Hongda Phytochemistry's manufacturing excellence can elevate your product quality and market competitiveness.