Griffonia Extract 5 Htp
2.Appearance: Off-White Powder
3.Specification: 98% 5-htp HPLC
4.CAS NO: 56-69-9
5.Packing Specification: 25kg/drum, 27 drums/tray
6.Delivery: 3-7working days
7.Certification: KOSHER,HALAL,BRC,ORGANIC,ISO9001,ISO22000 etc.
8.Main Market: European, North America, Asia
Griffonia Extract 5 HTP — Premium Botanical Supplement Ingredient for Sleep, Mood & Weight Management
Shaanxi Hongda Phytochemistry Co., Ltd. is a supplier of Griffonia Extract 5 HTP, which is standardised to 98% 5-HTP by HPLC and is derived from Griffonia simplicifolia seeds. Hongda was founded in 2001 and is a manufacturer of a 20,000 m² plant, 100,000-level purification workshops and an annual production of 3,000 tons. This substance directly penetrates the blood-brain barrier as a serotonin precursor, giving formulators a clean-label, non-synthetic alternative proven safe from Peak X contamination. Certifications BRC, ISO9001, ISO22000, ORGANIC, KOSHER, HALAL.
Product Introduction
Our product is a botanical substance derived from the seeds of Griffonia simplicifolia, a woody climbing shrub native to West Africa. It sends 5-Hydroxytryptophan (5-HTP), which is the direct metabolic precursor to serotonin, by-passing the rate limiting conversion step necessary for L-Tryptophan.
This makes it so much more bioavailable than normal tryptophan supplements. 5-HTP readily crosses the blood-brain barrier, which makes it a powerful regulator of mood, sleep cycle, and food cues.
Product Specification
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Item of Test
|
Limits of Test
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Results of Test
|
Method
|
|
Appearance
|
White Powder
|
White Powder
|
Visual
|
|
Odor
|
Characteristic
|
Characteristic
|
Visual
|
|
Assay by HPLC
|
5-htp≥ 99%
|
99.35%
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USP<197K>
|
|
Sulphated Ash
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<0.1%
|
0.05%
|
USP<467>
|
|
Loss on drying
|
<1.0%
|
0.26%
|
USP<467>
|
|
Heavy Metals
|
<10ppm
|
Conforms
|
USP<231>
|
|
As
|
<1. 0ppm
|
Conforms
|
USP<2232>
|
|
Pb
|
<1. 0ppm
|
Conforms
|
USP<2232>
|
|
Cd
|
<0. 05ppm
|
Conforms
|
USP<2232>
|
|
Hg
|
Negative
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Conforms
|
USP<2232>
|
|
Total Plate Count
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<1000cfu/g
|
73cfu/g
|
GB4789.2
|
|
Yeast & Mold
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<100cfu/g
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25cfu/g
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GB4789.15
|
|
E. Coli
|
Negative
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Absent
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GB4789.38
|
|
S. Aureus
|
Negative
|
Absent
|
GB4789.2
|
|
Salmonella
|
Negative
|
Absent
|
GB4789.4
|
|
Pesticides
|
Negative
|
Absent
|
GB4789.10
|
|
Conclusion
|
Conform with specification
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||
Third-Party Test Report
Shaanxi Hongda collaborates with several third party laboratories that are authorised globally for independent verification, such as SGS and Eurofins.
Each batch is checked for pesticide residue, heavy metals, microbiological, solvent residue and nutritional labelling. In the case of this product, each batch of Peak X (1,1'-ethylidenebis[L-tryptophan]) is assayed and confirmed to be below detection limits by HPLC.
In addition PAH (Polycyclic Aromatic Hydrocarbons) screening is undertaken because the raw material is wild-harvested. This safeguards your supply chain from FSMA or EU new food regulatory rejection.
COA (Certificate of Analysis)
A complete COA is provided with every shipment encompassing physical, chemical, microbiological and safety parameters:
· Physical tests: appearance, odour, bulk density, particle size
• Chemical testing : Assay by HPLC, Specific optical rotation , Loss on drying, Residual solvents (Ethanol/Methanol as per USP <467> )
· Safety testing: heavy metals, Peak X, PAHs, microbiology (Salmonella, E. coli, Staph)
COA is the USP and EP pharmacopoeia standards If you require a sample COA prior to ordering, please Contact Us directly.

Griffonia Extract 5 HTP Advantages
Clean-Label & Natural Origin
This extract is accompanied by a confirmed statement of natural origin. Griffonia Extract 5 HTP differs from biosynthetic fermented 5-HTP in that it possesses a natural isotopic signature, which can be confirmed by C14 testing, a need for premium EU and North American markets.
High Purity Testing
Genuine merchandise is distinguished from adulterated or spiked material by the 98%+ HPLC-verified purity. Accuracy of finished-product dosing requires such a degree of standardisation.
Bulk Density, Formulator Friendly
A bulk density of 0.45 to 0.65 g/ml is ideal for capsule and tablet filling machines, leading to reduced downtime in production and increased consistency of the fill.
# Food Grade Extraction
Processing employs just water and food-grade ethanol and is entirely compliant with EU Directive 2009/32/EC on extraction solvents. No harmful solvent residues.
Stability in normal conditions
Potency guarantyd 24 – 36 months when stored away from light and moisture (RH <60%) in vacuum sealed aluminium foil bags.

Griffonia Extract 5 HTP Application
Sleep Support Products
This substance is employed in capsule or tablet compositions sometimes paired with Melatonin and GABA. Its quick absorption profile reduces sleep latency and is especially helpful for those with circadian rhythm disorders.
Mood and Cognitive Blends
A natural fit for nootropic and mood support matrices as a serotonin-pathway constituent. The extract must be chemically stable with acidic B-Vitamins (particularly B6) and mineral adaptogens – a typical Hongda grade is sufficient for this purpose.
Weight Management Calculations
5-HTP is used in functional bars and meal-replacement shakes to help with satiety signalling. Microencapsulation is possible in such complex food matrices to protect potency throughout processing and to avoid harsh off-notes.
Production Process
Hongda’s extraction process is a controlled, traceable workflow:
1. Raw Material Selection – Seeds selected and screened by agronomists in supervised planting bases
2. Meat preparation – Cleaning, drying and size reduction
3. Water/Ethanol Extraction – Food grade solvents only; complies with EU Directive 2009/32/EC
4. Filtration & Concentration Multi-stage membrane filtration eliminates contaminants including Peak X isomers
5. Spray Drying – Produces a homogeneous off white crystalline powder of desired bulk density
6. QC Release Testing — HPLC assay, optical rotation, microbiological, heavy metals validated prior to Packaging
7. Packaging — PE bag within fibre drum, vacuum-sealed to protect from oxidation and moisture
Why Choose Us?
· Manufacturer since 2001 with 20,000 m² production facility
• 3,000 tons annual output with stable on-time delivery (3-7 working days)
· Laboratory in house with HPLC, GC, UV, Atomic absorption spectrophotometers - SGS standard
· Multi-certification portfolio: cGMP, FSSC22000, KOSHER, HALAL, BRC, ISO9001, ISO22000, ORGANIC (EU & NOP)
• Third party tested by SGS and Eurofins for each batch
· Full documentation on every shipment - Peak X testing on every batch

Our Certifications

Our Exhibitions

OEM / ODM Support
Shaanxi Hongda provides one-to-one product customisation for B2B buyers. Whatever you need:
Custom assay levels or particle size requirements.
· Micronized grades to facilitate suspension in liquid applications
· Bulk powder, capsules or tablets private label
· Blended formulae of 5-HTP with Melatonin, GABA or B6
Hongda’s R&D team consists of 20+ university-level experts that can build a formula to match your product concept. Production is carried out in a 100,000 level purification workshop under cGMP and FSSC22000 standards.
MOQ & Sample Policy Speak to our team directly.

FAQ
Q1: How do you know that your product is clear of Peak X contamination?
A: Advanced HPLC filtration is designed to target the Peak X isomeric impurity. Levels are non-detectable or below 10 ppm before any batch is shipped, as verified by release testing.
Q2: Can this extract be used in beverage applications?
A: Native 5-HTP is poorly soluble in water. Micronized grades are better suspended in liquids. Nano-emulsification or cosolvent systems are recommended for clear beverages to avoid sedimentation.
Q3: What is the difference between the product and Fermented 5-HTP?
A: Our product is botanically derived and has a clean natural-origin claim. Biosynthetic are fermented. Natural origin can be proven via C14 isotope testing.
Q4: Does the extraction employ toxic solvents?
A: No. Only water and food-grade ethanol are used, in complete compliance with EU Directive 2009/32/EC. The final powder has no leftover hazardous solvents.
Q5: What is the shelf life of the bulk powder?
A: 24-36 months when stored in original vacuum-sealed aluminium foil bags, protected from light and moisture (relative humidity less than 60%).
Q6. What documents do you supply to support regulatory submissions?
A: Full COA, third party SGS/Eurofins test reports, MSDS, specification sheet and certification documents (KOSHER, HALAL, ISO, ORGANIC) are available on request.
Contact Us
Ready to request a sample or discuss your formulation needs with Griffonia Extract 5 Htp? Email us at duke@hongdaherb.com
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