Premium Sodium Pyruvate Powder Manufacturer & Supplier | Shaanxi Hongda Phytochemistry

Since 2001, we have over 20 years of expertise developing pharmaceutical-grade biochemical compounds that meet the strict requirements of the biopharmaceutical research, cell culture applications, and medical aesthetics industries. Our Sodium Pyruvate Powder offers superior stability and purity (≥99% HPLC), tackling major industry issues including ammonia toxicity in bioreactors and oxidative stress in delicate cell lines. Unlike unstable liquid alternatives, our crystalline powder formulation offers longer shelf-life, easier logistics and constant performance throughout your production cycles. Partner with Shaanxi Hongda and benefit from cGMP-certified manufacturing, ISO22000-compliant quality processes, and extensive third-party testing to ensure every batch satisfies worldwide pharmacopeial requirements.

Product Introduction

Our sodium pyruvate bulk is the sodium salt shape of pyruvic acid, a key middleman of the mobile glycolysis and power metabolism pathways. This white crystalline chemical could be very soluble in water with solubility of greater than 47g in keeping with 100ml and a molecular weight of one hundred ten.04g/mol, which makes it suitable for quick dissolution in aqueous buffer structures. The powder is chemically more solid than liquid pyruvate alternatives, stored beneath managed situations, and does now not go through spontaneous polymerisation that could in any other case affect the integrity of the product.

Third-Party Test Report

Independent Laboratory Validation: Shaanxi Hongda engages with globally recognised testing organisations like SGS and Eurofins to undertake thorough analysis in addition to our own quality control measures. These third-party reviews reinforce our dedication to transparency and product quality.

Pesticide Residue Analysis: We conduct a multi-residue screening to ensure that levels of over 500 agricultural chemicals are non-detectable, in compliance with EU Regulation 396/2005 and FDA tolerance thresholds for pharmaceutical components – keeping your formulations compliant in all markets.

Laboratory

Sodium Pyruvate Powder Specification

Items	Specifications
Appearance	White or off-white crystalline powder
Assay	99.0%min
Pyruvic Ion	76%min
Free Acid	0.25% max
Loss on drying	0.5%max
Sulphate	400 ppm max
Chloride	100ppm max
Arsenic	1ppm max
Heavy metals	10ppm max
pH Value	5.1~7
Transparency	90%min

Please contact us to get COA and more information:duke@hongdaherb.com

Sodium Pyruvate Powder Advantages

Exceptional Purity Standards: The manufacturing technique gives regular assay values over 99% and eliminates contaminants that may intervene with enzymatic methods, enabling reproducible outcomes between experimental batches, a requirement for pharmaceutical development and regulatory filings.

Extended Shelf Life: Our non-hygroscopic model keeps loose-flowing residences and biochemical activity for 36 months underneath ambient garage settings as compared to hygroscopic variations that are vulnerable to caking and deterioration, accordingly lowering stock waste and purchase frequency.

Sodium Pyruvate Powder Application

Biopharmaceutical Cell Culture Systems: An alternative carbon source for CHO, HEK293 and hybridoma cell lines to bypass glycolytic lactate formation that acidifies culture environments and triggers apoptotic pathways in high density fed-batch fermentations. Used at 1-2 mM in serum-free and chemically defined media formulations such as DMEM and Ham’s F12.

Medical Aesthetic Formulations: Utilized in mesotherapy cocktails and chemical peel solutions at 2-five% concentrations, it promotes dermal fibroblast proliferation and collagen formation even as neutralising reactive oxygen species produced at some stage in tissue remodelling, effectively treating photoaging, melasma, and post-acne scarring in medical dermatology settings.

Production Process

Step 1 - Raw Material Selection and Preprocessing: The high purity pyruvic acid feedstock is subjected to a stringent incoming quality verification protocol. This includes identification confirmation by IR spectroscopy and purity determination by HPLC. This ensures only pharmaceutical grade beginning materials get into production, building the foundation of excellent final products.

Step 2 - Neutralisation Reaction: Pyruvic acid and sodium hydroxide are reacted in controlled stoichiometric ratios in temperature-controlled reactors at 15-25°C. Careful monitoring of the pH guarantees complete neutralisation without excess alkalinity, and the resulting Sodium Pyruvate Powder solution has the ideal ionic balance.

Step 3 - Purification and Filtration: The reaction mixture is processed through multi-stage activated carbon treatment and 0.22-micron sterile filtration systems located within Class 100,000 cleanroom facilities. This removes organic impurities, colourants and microbiological pollutants to provide pharmaceutical grade clarity.

Step 4 - Crystallisation and Drying: The purified solution undergoes controlled evaporative crystallisation in vacuum concentrators and fluid-bed drying at temperatures below 60°C (to avoid thermal damage). This yields a homogenous, crystalline powder that flows freely with a regulated particle size distribution and minimal residual moisture.

Step 5 - Quality Testing and Packaging: Every manufacturing batch is tested as per multi-compendial criteria earlier than double-sealed packaging in pe luggage in fibre drums. The nitrogen flush displaces the oxygen to keep away from oxidation and the items are stored in climate-controlled warehouses at temperatures between 15 and 25 stages celsius and relative humidity less than 60% until shipment.

Why Choose Us?

Shaanxi Hongda Phytochemistry combines the latest quality procedures and 20 years of experience in biochemical manufacture to ensure consistent product excellence. Our 20,000 square metre cGMP certified plant includes 100,000 level purified workshops and is operated under ISO9001, ISO22000 and FSSC22000 management systems, ensuring that each production step fulfils pharmaceutical industry requirements. With an annual manufacturing capacity of over 3,000 tonnes and smart inventory management in our 3,000-square-meter warehouse system, we ensure assured supply continuity and fast delivery within 3-7 business days worldwide. Our SGS standardised laboratory is equipped with HPLC, GC-MS, ICP-MS and microbiological analysis equipment and performs rigorous multi-parameter testing with over 20 PhD level scientists. Partnerships with Eurofins and SGS enable independent verification.

Our certifications

OEM / ODM Support

Custom Formulation Development: Our R&D team works with you to create proprietary blends of sodium pyruvate with synergistic compounds like alpha-ketoglutarate, carnitine or antioxidant complexes tailored to your specific application needs, whether it is for optimisation of cell culture performance or for new nutraceutical positioning.

Custom Packaging Options: We provide a variety of packaging options, from 100g bottles suitable for lab scale to 25kg drums for industrial use. Our packaging options include nitrogen-flushed aluminium foil bags, moisture-barrier containers and custom labelling with your branding, regulatory information and handling instructions in multiple languages.

Hongda Phytochemistry's Certifications

FAQ

Q: What is the recommended storage condition for your product?

A: Store in well sealed containers in cool, dry places at temperatures between 15-25°C and relative humidity below 60%. Keep away from direct sunlight and moisture. Under these conditions our product is stable for 36 months from date of manufacture.

Q: Do you have some smaller samples to send before ordering large size?

A: Definitely. We provide free samples of 50-100g in aluminium foil bags with full COA documentation, enabling you to assess quality and performance in your specific application before proceeding with production numbers.

Q: What’s your minimum order amount for standard packaging?

A: Our minimum order is 1 drum 25kg. However, we do make exceptions for smaller initial purchases for new clients and can explore flexible agreements depending on the size of your project and the required schedule.