Diosgenin Powder

Premium Diosgenin Powder Manufacturer & Supplier | High-Purity Phytosteroid Extract

Shaanxi Hongda Phytochemistry, a reliable manufacturer and supplier of high-quality Diosgenin Powder, provides you with great value for pharmaceutical and nutraceutical sectors across the globe. We have been providing you the gold standard precursor for steroid synthesis since 2001. With over 20 years experience we combine rigorous quality control and state of the art extraction technology to supply you with high purity product (specification 98%). Our modern factory with 20,000 square meters and 100,000 level purification workshops and SGS standardised laboratories assure you get consistent pharmaceutical quality material that fulfils international standards. By working with us, you receive access to reliable supply chains, competitive pricing of direct factory sourcing, and all-around technical support to help accelerate your product development cycles and reduce your production expenses.

Product Introduction

Diosgenin Extract Powder is a premium grade steroidal sapogenin from Dioscorea Zingiberensis rhizomes, scientifically characterised as C27H42O3, CAS number 512-04-9. This off-white crystalline powder is the starting material for the semi-synthesis of more than 60% of the world's steroid medicines, including corticosteroids and progesterone. Our 98% purity criteria enables excellent conversion efficiency in downstream processing. Our high quality parameters guarantee molecular integrity needed for medicinal applications. This high grade material with melting point range 204-208°C and excellent solubility in organic solvents fulfils the crucial industry demand for standardised API starting materials that provide consistent yields and minimise reaction difficulties.

Diosgenin Powder Advantages

High Purity Profile: With our state-of-the-art extraction and purification technologies, we provide purity levels of 98% or more. Every impurity you remove will only slow down your steroid conversion reactions and decrease your production yields.

Remarkable Structural Integrity: The maintained spirostan skeleton maintains the correct stereochemistry, ensuring the best reactivity for hormone production oxidative degradation processes.

Consistent Batch Reliability: Our team of R&D experts lead by our professors and automated production lines ensures batch-to-batch consistency to reduce formulation variability and shorten your regulatory approval timelines.

Improved Solubility Properties: The higher rates of dissolution in organic solvents are caused by the optimised particle size (80 mesh) and crystal structure, which leads to reduced reaction times and lower processing costs.

Extended Stability Window: With low moisture content (<0.5%) and negligible oxidative contaminants, our materials provide an extended shelf life to help safeguard your investment in inventory and reduce waste from material degradation.

Diosgenin Extract Powder Specification​​​​​​​

Third-Party Test Report

Full Quality Verification: We work with internationally recognised testing firms like as SGS and Eurofins to provide full transparency on your quality assurance needs.

Heavy Metal Analysis: Our product is stringently tested for lead, arsenic, mercury and cadmium, with findings consistently within EU and USP limits, confirming safety for pharmaceutical uses.

Pesticide Residue Screening: Multi-residue screening of over 500 pesticide chemicals to ensure compliance to European Pharmacopoeia regulations and protect your supply chain integrity.

Microbiological Safety: Our material undergoes Total Plate Count, Yeast, Mould, and Pathogen testing to ensure it fulfils pharmaceutical grade sterility criteria, removing contamination threats in sterile manufacturing settings.

Solvent Residue Analysis: GC analysis indicates the presence of residual solvents from extraction processes at very low levels, in conformity with ICH Q3C recommendations for pharmaceutical excipients.

Diosgenin Powder Application

Pharmaceutical Steroid Synthesis: Our Diosgenin Powder is an important starting material for the semi-synthesis of cortisone, pregnenolone and progesterone - the active ingredients in contraceptives and corticosteroids used around the world.

Nutraceutical Formulations: Included in dietary supplements for hormonal balance, menopause support and metabolic wellness, offering the natural benefits of phytoestrogens without the problems associated with synthetic hormone use.

Cosmeceutical Uses: Used in anti-aging skin care products for its collagen stimulating effects and its capacity to increase skin suppleness via hormone-like effects at the cellular level.

Veterinary Medicine: Precursor for animal health products for reproductive health and stress response in livestock and companion animals.

Research & Development: Academic and pharmaceutical research organisations use high purity material for the study of steroidogenesis pathways and new medicinal drug development.

Production Process

Step 1 - Raw Material Selection: We strictly choose high-quality Dioscorea Zingiberensis rhizomes from our own controlled planting bases. The cultivation process is in charge of competent agronomists to ensure that the diosgenin concentration is over 3.5%, preparing a superior foundation for the raw materials.

Step 2 - Washing and Preparation: The fresh rhizomes are cleaned by mechanical washing and cut with precision. This reduces the particle size to 2-3cm pieces, thereby increasing the surface area, which enhances extraction efficiency and removes soil pollutants and foreign materials.

Step 3 – Acid Hydrolysis Extraction: Sliced material is exposed to controlled acid hydrolysis at optimised temperature and pH conditions, breaking glycosidic linkages to release diosgenin aglycone from its saponin precursors, hence obtaining extraction rates over 95%.

Step 4 - Solvent Extraction and Separation: The hydrolysate is treated in a multi-stage organic solvent extraction using pharmaceutical grade ethanol, which selectively separates diosgenin and removes the plant colours, tannins and water-soluble contaminants by counter-current separation.

Step 5 - Crystallisation and Purification: The concentrated extract undergoes controlled cooling crystallisation leading to the formation of high purity diosgenin crystals. The crystals are washed with cold solvent to eliminate residual contaminants and their purity is confirmed by HPLC analysis reaching 98%+ purity.

Step 6 - Drying and Micronization: The purified crystals are introduced into vacuum drying chambers that keep temperatures below 60°C to retain the molecular structure. The crystals are then jet-milled to 80 mesh particle size, to ensure uniform dissolving properties.

Step 7 - Quality Testing and Packaging The final product is tested for over 15 criteria in our SGS-certified laboratory before being packed in double layer PE bags within fibre drums under regulated humidity settings to ensure stability throughout transit and storage.

OEM / ODM Support

Custom Specification Development: Together with you, our R&D team develops custom purity grades, particle sizes or extraction ratios that fully match the requirements of your particular formulation and your production processes.

Private Label Packaging: Full packaging customisation is available with your brand logo, product information and regulatory labelling on all formats from sample sizes to bulk drums to complement your market differentiation strategy.

Formulation Development Services: Leverage our formulators’ 20+ years of experience to develop custom blends that combine your product with synergistic chemicals to optimise bioavailability and therapeutic effectiveness for your needs.

Documentation Support for Regulatory: Obtain full technical files including Certificates of Analysis, Allergen Statements, BSE/TSE statements and regulatory compliance documentation necessary for your market registration activities.

MOQ Options: Negotiable: From 1kg samples to multi-ton contracts our varied inventory system supports small batch trial quantities for product development to large scale manufacturing volumes.

Supply Chain Integration: We synchronise production schedules to your demand projections, keeping strategic inventory reserves that provide just-in-time delivery and minimise supply interruptions impacting your manufacturing continuity.

Why Choose Us?

Shaanxi Hongda Phytochemistry offers high value by integrating the entire supply chain from the cultivation of raw materials to the delivery of completed products. We have 3000 tonnes per year of production capability, you will never be short of supplies. Our various International Certifications such as cGMP, FSSC22000, ISO22000, HALAL and KOSHER will help you access the world market. You get direct factory prices and avoid the middleman's markup. Your raw material expenses are up to 30% less than those of trading companies. Our technical team has the expertise of professors and is here to give you with ongoing application assistance, helping you to optimise your formulations and solve production difficulties. We prioritise your success and develop long-term collaborations based on quality consistency, transparent communication and dependable delivery performance, which has been acknowledged as a National High-tech Development Enterprise with 24-hour response time and dedicated account management.

FAQ

Q: What is the minimum order quantity?

A: Our typical MOQ is 25kg(1 drum), but we can also accept lesser quantities as samples starting from 100g for the purpose of initial testing and formulation development.

Q: How do you ensure consistent quality across different production batches?

A: Every batch undergoes 15+ quality control checkpoints, from the examination of the raw material to the release of the completed product. HPLC fingerprinting ensures batch-to-batch consistency within ±0.5% purity fluctuation.

Q: What is the typical shelf life and storage requirements?

A: Our product is stable for 24 months, when stored in sealed containers under cool (<25°C) and dry (<60% relative humidity) conditions, without substantial degradation.

Q: Can you provide organic or wildcrafted certification?

A: Yes, we offer ORGANIC (EU) and ORGANIC (NOP) certified options sourced from our certified planting bases, with complete traceability documentation upon request.

Q: What are the documents you offer for customs clearance?

A: We will prepare all the export documents, including Commercial Invoice, Packing List, Certificate of Analysis, Health Certificate, Phytosanitary Certificate and any other relevant documents for your destination country.

Q: Do you provide technical support for formulation development?

A: Yes, absolutely. Our technical staff will provide you with free formulation consultation on topics including solubility optimisation, stability testing methodologies and compatibility with other compounds in your formulation matrix.

Contact Us

Ready to elevate your product quality with premium Diosgenin Powder from a trusted manufacturer?

Get in touch today: duke@hongdaherb.com