Leucine Bulk Powder

L‑Leucine Bulk Powder | Fermentation‑Derived Essential Amino Acid Raw Material Supplier

We supply bulk fermentation‑produced Leucine Bulk Powder, one of the key branched‑chain amino‑acids for nutraceutical, functional‑food and pharma‑intermediate manufacturing. Many procurement teams reach out to us focusing on L‑isomer confirmation, consistent powder flow and lot‑to‑lot stability across large production runs.

We deliver food‑grade and compendial grades meeting USP / EP reference requirements. Every finished lot comes with lot‑tied COA, HPLC assay, optical‑rotation reading and full contaminant screening dataset. Lab‑evaluation samples and independent ISO‑17025 third‑party verification are available for manufacturers and ingredient distributors across global markets.

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Leucine Bulk Powder Advantages

​​​​​​​‑ CAS No.: 61‑90‑5, produced via controlled microbial fermentation

‑ Available grades: Food grade, USP grade, EP grade; HPLC Assay ≥98.5%

‑ Each shipment carries batch‑linked documents: COA, HPLC chromatogram, optical‑rotation result, related amino‑acid impurity panel, heavy‑metal & microbial screening

‑ Evaluation samples:100‑500g, sealed inside moisture‑barrier Packaging

‑ Accept independent third‑party analysis at buyer‑nominated ISO‑17025 laboratory

‑ Moisture‑resistant 25kg fiber‑drum bulk‑packaging; custom particle‑size / bulk‑density screening can be arranged for large‑volume orders

Product Specification

Important manufacturing note: For manufacturing and laboratory use only. Not intended for direct consumer intake.

Leucine Bulk Powder Benefits

Sports Nutrition Supplements: The main active ingredient in BCAA formulations, often at 2:1:1 ratios, used to enhance muscle protein synthesis and workout recovery.

Clinical Nutrition Products: Roles in medicinal foods for sarcopenia, cachexia, and age-related muscle wasting diseases.

Functional drinks: Ideal for ready-to-drink protein drinks and meal replacement shakes in need of instantized amino acid profiles.

Animal Nutrition: Formulates better feeds for livestock and companion animals, resulting in better growth rates and feed conversion efficiency.

Manufacturing process

Step 1 – Microbial FermentationSelected strains of Corynebacterium glutamicum are cultured in controlled aerobic fermentation in 5,000L bioreactors and converted into L-Leucine at a >50g/L concentration and biotechnological efficiency, with no petrochemical dependencies.

Step 2 – Multi-stage Purification The cell-free fermentation broth is passed via ion-exchange chromatography columns and activated carbon filtration beds to remove endotoxins and pigments to achieve pharmaceutical-grade purity of >99%

Step 3 – Crystallisation and Drying: The concentrated leucine solution is crystallised by controlled cooling, then separated by centrifugation and dried in a fluid-bed dryer at carefully controlled temperatures to produce homogeneous crystalline particles with optimised bulk density.

Step 4 – Quality Check: Each batch of Leucine Bulk Powder is subjected to a 17-point quality inspection at our SGS-certified laboratory, which includes HPLC assay, residual solvent analysis, and microbiological testing, before getting batch release permission.

Third Party Test Report

Purity Verification: Independent SGS testing verifies ≥99.0% L-Leucine content using HPLC technique, with enantiomeric purity >99.5% L-form.

Heavy Metal Screening: Testing by Eurofins shows lead <0.5ppm, arsenic <0.3ppm, cadmium <0.2ppm and mercury <0.1ppm, far within FDA and EU regulatory limits.

Microbiological Safety: Total plate count <1,000 cfu/g Yeast and mould <100 cfu/g Salmonella, E. coli and Staphylococcus aureus negative in 25g.

Why Choose Us

Shaanxi Hongda Phytochemistry offers best-in-class value with end-to-end integration from raw material cultivation to final product delivery. We have three specialised planting bases to assure ingredient traceability, and 150 skilled technicians to ensure production uniformity across 10 sophisticated manufacturing lines, with an annual output of 3,000 tonnes. Since we don’t trade, we remove the middlemen, and with our 3,000 square metre warehouse and six specialised storage zones, we have everything ready for you immediately. Our professor-led quality team and cooperation with SGS and Eurofins will provide you the analytical rigour you need for competitive differentiation in premium nutrition markets.

Documents delivered with bulk shipment include batch‑tied COA, HPLC chromatogram, optical‑rotation report and SDS safety‑data sheet. Halal / Kosher copies are available for eligible lots upon request. Our facility holds ISO22000 certification. We fully support third‑party lab verification if your QA department requires external validation.

OEM/ODM Service

Custom Formulation Development: Our 20 person R&D team interacts with your technical team to produce customised amino acid blends using synergistic compounds such as beta alanine or citrulline for better performance results.

Flexible Packaging Solutions: We provide a variety of packaging solutions to suit all your needs, including 1kg aluminium foil bags for sample and trials, and 500kg supersacks for large-scale production, all produced in pharmaceutical-grade cleanrooms.

Regulatory Documentation: Each delivery includes a complete Certificate of Analysis, stability studies, allergy declarations, and BSE/TSE statements to ease your regulatory filing procedure in worldwide markets.

Private Labelling Services: We provide complete turnkey solutions including capsule filling, tablet pressing, and sachet packaging with your brand, all inside our cGMP-certified manufacturing facilities.

Packaging, MOQ & Lead Time

Packaging

‑ Evaluation sample unit: Moisture‑barrier vacuum‑sealed foil pouch ‑ Bulk shipment: 25kg moisture‑proof fiber‑drum fitted with dual food‑grade inner plastic bags. Custom labels are available on large‑volume orders.

Order Information

‑ Evaluation sample：100‑500g for lab formulation assessment

‑ MOQ：1kg for trial batch; 25kg for standard bulk shipment

‑ Sample lead‑time：4‑6 working days

‑ Bulk production lead‑time：8‑16 working days, subject to production scheduling and raw‑material feedstock condition

‑ Shipping options: Air express for small consignments; sea‑freight for bulk‑volume orders

Practical business note: For multi‑ton large‑volume orders, send inquiry well ahead so we can lock production slot and secure raw‑material stock against commodity price swings.

Guidance For Formulation Engineers

L‑Leucine powder dissolves moderately in water‑based matrices. Workshop humidity should stay controlled during blending and filling workflow to minimise caking risk.

When you produce tablets, powder sachets or BCAA premix blends, particle‑size and bulk‑density parameters affect powder flow, dust level and mixing homogeneity. Reach out early if you need adjusted mesh screening for your production setup.

When compounding with other amino‑acids for custom premix, carry‑out homogeneity trials using your real production equipment before scaling‑up commercial batches.

FAQ

Q: What is the minimum order quantity for bulk purchases?

A: Generally our MOQ is 100kg, however for the first trial order we may start from 25kg for qualified manufacturers.

Q: Do you have samples for formulation testing?

A: Yes, we give free samples of 100g with full COA documents to serious purchase enquiries, by express courier, within 3-5 working days.

Q: How do you achieve batch to batch consistency?

A: Our ISO9001-certified quality management system mandates retention samples from every production lot, with comparative HPLC fingerprinting to maintain ±0.5% variance in active content.

Q: What documents are needed for overseas shipping?

A: Each cargo contains a Commercial Invoice, Packing List, Certificate of Analysis, Health Certificate, Non-GMO Declaration, and other documentation upon your request for customs clearance.

Q: Do you offer technical support for formulation challenges?

A: Our applications team provides complimentary consultation on solubility enhancement, flavor masking, and stability optimization throughout your product development cycle.

Contact Us

Ready to elevate your formulation with premium Leucine Bulk Powder from a certified manufacturer? Contact our international business department at duke@hongdaherb.com  to discover how our two decades of amino acid manufacturing excellence can strengthen your supply chain and accelerate your product innovation timeline.