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Luteolin Extract

1.Botanical Source: Sophora japonica L.
2.Appearance: Light Yellow Powder
3.Specification: Luteolin 98%
4.Test Method: HPLC
5.CAS NO: 491-70-3
6.Main Market: European, North America, Asia
7.Packing Specification: 25kg/drum, 27 drums/tray
8.Delivery: 3-7working days
9.Certification: KOSHER,HALAL,BRC,ORGANIC,ISO9001,ISO22000 etc.

Premium Luteolin Extract Manufacturer & Supplier - High-Purity Natural Flavonoid Ingredient

We offer outstanding value through vertical integration, from the cultivation of raw materials in our own Sophora japonica planting bases to the final extraction in our 100,000-level purification facilities, with over 20 years of experience since 2001. Our superior HPLC-verified Luteolin Extract is up to 98% pure, delivering a clean-label product that meets key industry needs for natural anti-inflammatory and neuroprotective agents. Partner with Hongda for certified quality (cGMP, FSSC22000, ISO22000), ensure your formulations meet international market needs, benefit from the continuous innovation of our professor-led R&D team, and rely on our supply chain with 3,000+ tonne annual capacity.


Luteolin Supplier

Luteolin powder is a premium bioactive flavonoid ingredient derived from buds of Sophora japonica with our patented technology of low temperature extraction. This light yellow powder is 3',4',5,7-tetrahydroxyflavone which is its main active component providing excellent anti-inflammatory and antioxidant characteristics. Our extraction procedure retains the natural integrity of this potent chemical while obtaining pharmaceutical grade purity levels. The substance is very stable under processing circumstances and has great blood brain barrier penetration, making it ideally suited for advanced neuro-cognitive formulations.

Compound
Percentage Composition
Luteolin
≥ 98%
Other Flavonoids
≤ 2%

Luteolin powder


Third-Party Test Report

Independent Verification: Our product undergoes rigorous third-party testing through internationally recognized laboratories including SGS and Eurofins, ensuring complete transparency and quality assurance for your supply chain.

Pesticide Residue Analysis: Comprehensive multi-residue screening confirms compliance with EU regulations (EC 396/2005) and USDA organic standards, with all tested compounds below detection limits, safeguarding your product's clean-label positioning.

Heavy Metal Screening: Atomic absorption spectrophotometry verifies that lead, arsenic, cadmium, and mercury levels meet stringent international thresholds, typically showing results well below 10 ppm total heavy metals, protecting your consumers and brand reputation.

Laboratory

Luteolin Extract Advantages

Enhanced Bioavailability: Micronised extraction process generates ultra-fine particles with D90 < 10 microns, dramatically increasing the rate of solubility and absorption efficiency in your formulations vs. standard coarse powders.

Exceptional Purity Standards: 98% luteolin content using sophisticated chromatographic separation to remove interfering substances, providing concentrated efficacy to lower required dosages and increase cost-effectiveness for your completed products.

Heat Stability Profile: Our Sophora japonica extract is more heat stable than anthocyanins and other sensitive flavonoids and does not degrade at temperatures up to 180°C during typical manufacturing procedures, allowing greater flexibility in formulation for tablets, capsules and functional beverages.


Luteolin Specification

ITEM
SPECIFICATION
TEST METHOD
Physical Description
Appearance
Light Green Powder
Visual
Odor
Characteristic
Organoleptic
Taste
Characteristic
Olfactory
Bulk Density
50-60g/100ml
CP2015
Particle Size
95%-99% through 80 mesh
CP2015
Chemical Tests
Luteolin
≥98%
HPLC
Loss on Drying
≤1.0%
CP2015 (105 oC, 3 h)
Ash
≤1.0%
CP2015
Total Heavy Metals
≤10 ppm
CP2015
Cadmium (Cd)
≤1 ppm
CP2015(AAS)
Mercury (Hg)
≤1 ppm
CP2015(AAS)
Lead (Pb)
≤2 ppm
CP2015(AAS)
Arsenic (As)
≤2ppm
CP2015(AAS)
Microbiology Control
Aerobic Bacterial Count
≤1,000 cfu/g
CP2015
Total Yeast & Mold
≤100 cfu/g
CP2015
Escherichia Coli
Negative
CP2015
Salmonella
Negative
CP2015
Staphylococcus Aureus
Negative
CP2015

Contact us today to discuss your requirements, request samples, or learn more about our customization capabilities. Let us help you create exceptional products with our high-quality natural extracts:duke@hongdaherb.com.


Luteolin Extract Application

Neuro-Cognitive Supplements: Develop premium brain health supplements that combat age-related cognitive decline and neuroinflammation, using luteolin’s microglial regulation to deliver real improvements in memory retention and mental clarity for ageing populations.

Anti-Inflammatory Wellness: Develop natural solutions for joint health and managing systemic inflammation, utilising luteolin's COX-2 inhibition as a safer, natural alternative to synthetic NSAIDs for long-term consumer usage.

Clinical Skincare Formulations: Develop innovative dermo-cosmetic formulations for sensitive skin disorders such as rosacea and dermatitis. Luteolin’s mast cell stabilising and UV-protective effects can be used to lower inflammatory indicators and photo-aging.


Production Process

Step 1 - Raw Material Selection: Our agronomists pick mature Sophora japonica buds at the best luteolin concentration periods, drying immediately at controlled temperatures. Timing is done carefully to preserve maximum flavonoid concentration yet prevent enzymatic breakdown.

Step 2 - Pre-treatment & Extraction: Raw materials are selected, cleaned, and sized to an ideal particle size, then macerated in a food-grade ethanol-water solution at specified ratios. This technique solubilises target molecules efficiently while coextracting minimal unwanted components.

Step 3 - Filtration & Concentration: The extract solution is filtered through multi-stage filtration systems to remove particles and plant debris, followed by vacuum concentration at decreased temperatures.

Step 4 - Purification & Crystallisation: Employing advanced column chromatography to isolate luteolin from residual impurities by exploiting variations in polarity, followed by controlled crystallisation techniques.

Step 5 - Drying & Micronization: Purified crystals are spray-dried or vacuum-dried to remove any remaining moisture and are jet-milled to provide a homogenous particle distribution. This final treatment ensures excellent fluidity, dissolving properties and biological availability.

Production process

Why Choose Us?

Vertical integration advantage: We are not trading firms, we are in charge of all production stages, from our approved planting bases to final packing. This means no intermediaries, traceability, quality consistency and competitive prices that immediately benefit your bottom line.

Cutting-Edge Research Capability: We work with academic research institutions and 20+ PhD scientists to continuously improve extraction efficiency, bioavailability enhancement and creative application development, keeping your products at the forefront of market trends.

Our team

Full Certification Portfolio: cGMP, FSSC22000, ISO22000, BRC, HALAL, KOSHER, EU Organic and NOP Organic Certifications in 2025. We offer turn-key solutions for the most demanding regulatory environments around the world.

Certifications

OEM / ODM Support

Custom Formulation Development: Our professor-led R&D team works directly with your technical personnel to produce customised mixes combining Luteolin Extract with complimentary substances, optimising synergistic effects for your specific therapeutic aims and market positioning.

Flexible Format Options: We produce your custom formulations in a wide array of delivery systems such as hard capsules, soft gels, tablets with special coatings, water-soluble premix powders and concentrated liquid extracts to meet a wide range of consumer preferences and application needs.

Private Label Packaging: Select from our diverse packaging choices or send in your bespoke designs for bottles, pouches and cartons, including professional graphics integration and multilingual labelling that fulfil regional regulatory needs for North America, Europe and Asia markets.

OEM Service

FAQ

Q: What makes your product superior to standard plant extracts?

A: Our extract is 98% pure extract due to improved chromatographic separation vs 20-50% of crude extracts. This concentration results in much greater efficacy per gram, allowing for lower doses and better formulation economics, all with consistent batch-to-batch performance.

Q: How do you approach the issue of water solubility in aqueous formulations?

A: We can offer micronised powder with sub 10 micron particles for better dispersion, and can customise phospholipid complexes or cyclodextrin inclusion complexes that greatly boost water solubility. Our technical staff will provide precise recommendations on your formulation matrix.

Q: Do you send samples for formulation experiments before bulk ordering?

A: Of course. We can provide samples of 20-100 g in sealed aluminium foil packaging with full COA. Samples are shipped within 48 hours by express courier so you may do extensive compatibility and stability testing before committing to production quantities.


Contact Us

Ready to enhance your product formulations with premium Luteolin Extract backed by world-class manufacturing and responsive partnership support?

Email: duke@hongdaherb.com

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