Hesperidin Powder Bulk

Hesperidin Powder Bulk — High-Purity Citrus Extract for Pharmaceutical & Nutraceutical Manufacturing

Shaanxi Hongda Phytochemistry Co., Ltd. supplies Hesperidin Powder Bulk at 95% purity (HPLC), extracted from Citrus aurantium L. (CAS 520-26-3). As a manufacturer with 20,000 m² facility, 3,000-ton annual output, and Certifications including Kosher, Halal, FSSC22000, cGMP, ISO9001, and ISO22000, we deliver batch-stable, pharma-grade bioflavonoid raw material. Each batch is tested in-house and verified by SGS and Eurofins, covering purity, heavy metals, pesticide residues, and microbiology. From R&D formulation support to OEM customization, Hongda gives B2B buyers a direct factory source with full documentation.

Product Introduction

Hesperidin, a natural flavonoid glycoside (flavanone-7-o-glycoside), is present in the exocarp of citrus fruits. It is sometimes called Vitamin P. The molecular weight of the chemical is 610.56 g/mol and the molecular formula is C28H34O15.

Our bulk hesperidin is standardised to ≥95 % purity by HPLC, ideal for pharmaceutical, nutraceutical and cosmeceutical use. It is a fine powder of light yellow to brown-grey in colour and has a melting point between 258°C and 262°C, which is a proof of thermal stability for heat-intensive production.

The natural water solubility of the product is low. Micronization technology (D90 < 10-20 microns) or alkali co-processing may be employed if the dissolving rate in gastrointestinal settings is a formulation requirement.

Third-Party Test Report

Each production batch is independently tested by authorised third party laboratories such as SGS and Eurofins. Test scope is: .

· Pesticide residue screening

· Nutrition label verification

· Optical rotation (chiral identity validation)

· Report of natural origin

· Custom testing as required by buyer

This two-tiered system of testing — internal HPLC/GC/UV analysis plus external third-party confirmation — assures that each shipment matches the certificate of analysis.

Product Specification

Hesperidin Powder Bulk Advantages

High Purity, HPLC-Verified

Our Hesperidin Powder Bulk has an assay of ≥95% by HPLC with chemical fingerprinting to rule out adulteration with related citrus flavonoids such as Naringin. Each lot is traceable from raw material to the finished powder.

Thermal and processing stability

The melting point of 258 degC-262 degC indicates a good performance of the material in high temperature tabletting, encapsulating or spray drying processes without decomposition.

Synergistic Compatibility of Formulations

Hesperidin acts with Vitamin C and Diosmin. It slows down the destruction of ascorbic acid and decreases capillary permeability - often included in venous insufficiency preparations with the Diosmin/Hesperidin 90:10 ratio.

Choice of flexible particle size

Standard 80 mesh for tablet and capsule mixtures. Available for clinical MPFF formulations or topical serums where particle size is directly related to bioavailability and emulsion stability, micronized grade (D90 < 10 microns) is obtainable.

Full Documentation Pack

Buyers get COA, MSDS, specification sheet, third party test results and regulatory certificates – ready for FDA, EU and APAC market submission.

Hesperidin Powder Bulk Application

1. Pharmaceutical Venotonics (MPFF)

Combined with Diosmin in a 90:10 ratio for the treatment of Chronic Venous Insufficiency (CVI) and haemorrhoids. This application requires EP/USP grade purity, tight microbiological limits and validated residual solvent levels per ICH Q3C.

2. Sports Nutrition & Cardio Supplements

Also included to heart-health and pre-workout blends to increase synthesis of endothelial Nitric Oxide synthase (eNOS). Uniform blending with hygroscopic co-ingredients, such as Citrulline or Arginine, requires a constant mesh size.

3. Cosmeceuticals Topicals

Utilised in serums and lotions for dark circles and uneven skin tone. The mechanism is based on the improvement of cutaneous microcirculation and inhibition of tyrosinase activity. Ultra-fine particle size and neutral colour are required for the white emulsion look.

OEM / ODM Support

Shaanxi Hongda serves B2B buyers looking for more than raw powder with comprehensive OEM and ODM customisations. You can choose from:

• Available in custom purity levels of 90%, 92%, 95%, and 98%.

· Custom particle size standard mesh or micro-fine

· Dosage forms: soft gels, hard shell capsules, tablets, pre-mixed powders

· Private label Packaging: custom printed drums, foil packs, or ready-to-retail formats

· Small sample quantities: 20-100 g samples available in aluminium foil packs before you commit to a big order

From the first enquiry to the final shipping, your dedicated account manager will organise formulation, testing and paperwork.

Why Choose Us?

· Factory Direct price – No middlemen, 3,000-ton capacity per year for competitive bulk price

· Founded in 2001 – more than 20 years of experience in the production of plant extracts

· Certified supply chain – cGMP, FSSC22000, ISO9001, ISO22000, Kosher, Halal, BRC, FDA, Organic (EU & NOP)

• In-house + 3rd party QC – internal lab with standards from SGS and external verification from Eurofins

• Fast shipping – 3-7 working days for typical orders

· R&D Team – 20+ Scientists for Custom Formulation & New Product Development

Production Process

Shaanxi Hongda adopts a closed-loop extraction technology in a 100,000-level purification workshop The process comprises these critical steps:

1. Raw material sourcing – Citrus aurantium peels from controlled planting bases under agronomist supervision

2. Solvent Extraction — Ethanol/water system (within ICH Q3C residual solvent limits)

3. Filtration & Concentration Membrane filtration for contaminants removal

4. Recrystallization & Purification To achieve ≥95% assay goal

5. Drying & Milling - Spray or vacuum drying. Standard or micronized sizing.

6. QC Testing & Release HPLC, ICP-MS heavy metal, microbiological pre-release

7. Package: Double PE inner bag, fibre drum, 25kg/drum.

FAQ

Q1: What is the usual purity of your bulk hesperidin?

A: Our specification is >=95% by HPLC. We can also offer 90% and 98% grades based on application and budget.

Q2: Is your hesperidin from Citrus aurantium or Citrus sinensis?

A: It is extracted from Citrus aurantium (Bitter Orange). Immature peels are more rich in flavonoids. The source is tracked on the COA and substantiates accurate label claims in your target market.

Q3: Does this stuff work on clear liquid drinks?

A: Bulk powder is not water soluble and will settle out in clear liquids. In such application, enzymatically modified hesperidin (alpha-glucosyl hesperidin) or nano-emulsion processing is required.

Q4: How can you control the colour difference of batch?

A: Slight colour variations from bright yellow to brown-gray may occur due to natural seasonal variation in citrus harvest. Colour is maintained within the approved commercial range via consistent extraction techniques and lot blending.

Q5: Which residual solvent standards do you adhere to?

A: Ethanol extraction is utilised; residual solvent levels adhere to ICH Q3C criteria for Class 2 and Class 3 solvents. The results are reflected in the third party test report.

Q6: What is the minimum order quantity of the product?

A: MOQ is 25kg (1 drum standard) 20-100 g samples available prior to bulk order.

Contact Us

Ready to source Hesperidin Powder Bulk for your next project? Send your inquiry to duke@hongdaherb.com.