Bergenin Powder

Premium Bergenin Powder – Professional Manufacturer & Supplier

Shaanxi Hongda Phytochemistry Co., Ltd. is a professional manufacturer and supplier of high purity and high quality Bergenin Powder to global pharmaceutical, nutraceutical and cosmetic industries. Since 2001, we have specialized in the production of natural plant extracts using modern extraction technologies and strict quality control procedures. Our product is in compliance with worldwide pharmaceutical standards, with purity levels up to 98%-99%. We are certified by cGMP, FSSC22000, HALAL, KOSHER and ISO22000. We have 20,000 square metre contemporary facility, 100,000 level purification workshops and SGS standardised laboratory to guarantee every batch of potency and safety. Choosing Hongda means you are sourcing traceable raw materials from our organic planting bases, with thorough third-party testing and speedy delivery within 3-7 working days, allowing your products with trustworthy bioactive ingredients that address key formulation difficulties.

Bergenin Supplier

Bergenin extract is a bioactive C-glycoside molecule isolated from the rhizomes of Bergenia species, which are of interest for medicinal and cosmetic uses. Shaanxi hongda phytochemistry's bergenin is a white crystalline powder this is used as a non-narcotic antitussive agent in respiratory formulations, and as a solid pores and skin-brightening element in beauty products. It has the chemical formula C14H16O9 and the CAS number 477-90-7 and it provides a better stability than oxidative polyphenols. Premium grade powder. Purity ≥98% (HPLC confirmed). Heavy metals ≤10ppm. Easily soluble in hot ethanol and methanol for flexible formulation with consistent therapeutic efficacy to support your product development needs.

Product Extraction Process

Third Test Report

Independent Verification for Export Compliance: We partner with internationally recognized laboratories including SGS and Eurofins to provide comprehensive third-party testing reports that meet EU and USA regulatory standards.

HPLC Purity Test: Each batch is analysed by high-performance liquid chromatography to determine active content ≥98.0%, assuring accurate dose for medicinal use.

Heavy Metals Analysis (ICP-MS): We test to regulate Arsenic (As), Lead (Pb), Mercury (Hg) and Cadmium (Cd) with total limits ≤10ppm, to ensure safety for topical and internal use.

Residual Solvent Detection: Headspace gas chromatography detects residual methanol and ethanol 5000ppm, completely complying with ICH Q3C requirements for pharmaceutical grade substances.

Microbiological Safety: Specialised culture testing to ensure end-user health by detecting no E. coli, Salmonella or Pseudomonas aeruginosa.

Pesticide Residue Screening: Multi-residue screening of 500+ compounds to assist you in meeting international standards of food safety and organic certification criteria.

Product Specification

Please contact us to get COA and more information:duke@hongdaherb.com.

Bergenin Powder Advantages

Non-Narcotic Respiratory Solution: Our powder is a potent cough suppressant that does not depress the central nervous system or have addictive effects, unlike codeine-based antitussives. This makes it suitable for treating chronic bronchitis and for use in paediatric formulations.

Enhanced Expectorant Activity: Stimulates secretion from tracheal glands and thins thick mucus. Addresses the problem of inefficient sputum clearance in respiratory infections where standard expectorants are ineffective.

Stable Skin Brightening Agent: Addresses the cosmetic industry’s problem concerns by blocking the activity of tyrosinase without the oxidative instability of Vitamin C or the cytotoxicity of Hydroquinone, ensuring safe melanin reduction for long-term use.

Excellent Thermal Stability: Melting Point 232-240°C. It withstands conventional manufacturing temperatures and no deterioration happens during tablet compression or encapsulation operations.

Broad Formulation Compatibility: Balanced solubility profile enabling integration in aqueous and lipid-based systems, decreasing formulation development time and broadening application options across product categories.

Bergenin Powder Application

Pharmaceutical Cough Preparations: Primary ingredient for syrups, lozenges, & tablets for chronic cough & bronchitis, excellent alleviation without narcotic schedule distribution issues.

Respiratory Health Supplements: Featured in natural wellness products supporting lung function and mucus clearance, appealing to health-conscious consumers seeking plant-based alternatives to synthetic drugs.

Skin Whitening Cosmetics: Key active ingredient in serums, creams and masks for treatment of hyperpigmentation, melasma reduction and overall complexion whitening with validated safety profiles.

Anti-Aging Skincare: Incorporates anti-oxidant qualities to fight free radicals and protect skin from environmental aggressors and premature ageing in premium formulas.

Modernisation of Traditional Medicine: Standardises herbal treatments with Bergenia extracts for pharmaceutical production standards, maintaining traditional therapeutic benefits for the worldwide market.

Step 1 – Raw Material Selection: Our agronomists pick Bergenia rhizomes from certified organic planting bases during the optimum development time. Result: Full traceability documentation and guaranteed high bergenin content.

Step 2 – Cleaning and Pre-treatment: Fresh rhizomes are cleaned by mechanised washing and enzymatic inactivation at controlled temperatures. Results: Soil pollutants were eliminated without loss of bioactive compounds integrity.

Step 3 – Extraction Operation: The crushed material undergoes an optimised ethanol extraction process in stainless steel reactors with counter-current circulation systems. Result: Maximum production of bergenin with minimum use of solvent.

Step 4 – Filtration and Concentration: Multi-stage filtration eliminates plant fibres, then hoover concentration at lower temperatures. Protected thermally sensitive molecules and concentrated active components in clarified extract.

Step 5 – Crystallisation and Purification: Controlled cooling causes the formation of bergenin crystals, which are then subjected to several cycles of recrystallisation. Result: Pharmaceutical grade purity ≥98% with constant crystal shape

Step 6 – Drying and Milling: Crystals are dried in vacuum furnaces and micronised by jet milling in a clean chamber at the 100,000 level. Result: Fine powder, homogenous particle size distribution and regulated moisture content < 5 %

Step 7 – Quality Testing & Packaging: The complete batch is subjected to extensive analysis at our SGS laboratory before being nitrogen sealed and packed in double layer PE bags in fibre drums. Verified requirements with longer shelf stability for global delivery.

OEM / ODM Support

Custom Formulation Development: Our 20+ PhD-level experts work alongside your team to design custom mixes of bergenin and complementing actives to create unique products that distinguish your brand in competitive marketplaces.

Flexible Specification Options: We provide bergenin powder in several purity grades (95%-99.5%) and particle sizes, customised to meet the exact needs of your application, from direct compression tablets to nano-emulsion systems.

Customised Packaging Solutions: We customise packaging materials, designs and labelling from bulk 25kg fibre drums to consumer-ready sachets and capsules to fit your brand identity and regulatory requirements in various regions.

Private Label Manufacturing: Full turnkey service including formula optimisation, stability testing, regulatory documentation preparation, and finished product manufacturing under your brand, dramatically speeding your time-to-market.

Technical paperwork Support: We can supply full DMF (Drug Master Files), CMC paperwork and analytical method transfer packages to help you with regulatory approval processes in target markets.

Why Choose Us?

23 Years of Manufacturing Experience: Over 20 years experience in extraction technologies and quality systems, providing an in-depth understanding of botanical chemistry, and consistency of product and technical problem solving.

Cutting-edge Infrastructure: We provide current extraction lines, 100,000-level purification workshops and advanced analysis instruments including HPLC, GC, ICP-MS, to ensure the production meets pharmaceutical standards in every aspects.

Advantage of Vertical Integration: We have three dedicated planting bases in high mountain areas, and we manage the full supply chain from seed selection to final packaging, ensuring the quality of raw materials and stable prices.

Full Certification Portfolio: We have Certifications of cGMP, FSSC22000, HALAL, KOSHER, BRC, ORGANIC (EU/NOP), ISO9001 and ISO22000, which shows our dedication to satisfy different international requirements for worldwide market access.

Professional Service Team: Our more than 200 devoted experts, including quality specialists, R&D scientists and multilingual customer service representatives, provide rapid support, technical guidance and seamless communication throughout your project lifecycle.

Flexible Order Fulfilment: Our 3,000 square metre climate-controlled warehouse and large inventory allow us to fulfil orders from sample amounts to multi-ton shipments with consistent 3-7 day delivery schedules internationally.

FAQ

Q: What is the minimum order quantity for the product?

A: We accept orders starting from 1kg for initial testing, and we offer low prices for bulk orders above 100kg for research and commercial scale production.

Q: Can we send samples before bulk order?

A: Definitely. We provide 20-100g samples in aluminium foil bags with full COA documentation so you may check quality and compatibility with your composition before placing larger orders.

Q: How do you keep the quality the same on each batch?

A: Each batch of production is manufactured as per standardised operating procedures with in-process controls. Each batch is fully panel tested as per USP/CP standards and validated against retained reference standards to ensure batch to batch consistency within ±2% deviation.

Q: How long will it last and how should it be stored?

A: The product is stable for 24 months with low degradation of active substance when maintained in sealed containers at room temperature (15-25°C), protected from light and moisture.

Q: Do you help with the regulatory paperwork of various countries?

A: Yes, our regulatory affairs team prepares customized documentation packages including Certificates of Analysis, Allergen Statements, GMO-Free Declarations, and Health Certificates tailored to specific country requirements for FDA, EFSA, or other authorities.

Q: Can this product be used with other active ingredients?

A: Our R&D team conducts compatibility studies to generate stable multi-component formulations including physical stability and chemical interaction and synergism to optimise your product performance.

Contact Us

Ready to enhance your product line with premium Bergenin Powder backed by professional manufacturing excellence?

Email: duke@hongdaherb.com​​​​​​​