Honeysuckle Extract Benefits

What is Honeysuckle Extract?
Wholesale Organic Honeysuckle extract, which is extracted from the flower buds and early blooming flowers of the perennial semi-evergreen twining plant Lonicerae Lonicera, contains a variety of plant active ingredients that are beneficial to the human body, such as chlorogenic acid, isochlorogenic acid, and luteolin Flavonoids, such as flavonoids, have strong anti-tumor, physical fitness, anti-virus, antibacterial, and skin conditioning effects. Chlorogenic acid from honeysuckle powder is widely used in the fields of medicine, daily chemicals, and food.

So, what is honeysuckle extract chlorogenic acid?
Chlorogenic acid (CGA), also known as coffee tannin, is a condensed acid formed from eafeic acid and quinic acid, and belongs to phenylpropanoid compounds. CGA widely exists in plants, mainly in honeysuckle and Eucommia, and has a wide range of pharmacological effects.

Physicochemical properties of chlorogenic acid:
Chlorogenic acid hemihydrate is white or yellowish needle-like crystal, which becomes anhydrous at 110°C, and dissolves with dilute hydrochloric acid to produce caffeic acid, with a melting point of 208°C. Chlorogenic acid has a solubility of about 4% in water at 25°C. It is easily soluble in polar solvents such as ethanol, acetone, and methanol, slightly soluble in ethyl acetate, and hardly soluble in lipophilic organic solvents such as chloroform, ether, and benzene. Chlorogenic acid is an ester of caffeic acid and quinic acid. Due to the special structure of chlorogenic acid, it is determined that chlorogenic acid can be extracted by polar solvents such as ethanol, propanol and methanol, but chlorogenic acid itself is unstable, and the temperature cannot be adjusted and heated for a long time during extraction.

Pharmacokinetics of chlorogenic acid:
Studies have shown that the oral effect of chlorogenic acid is poor, only a small part can be absorbed in the small intestine, and most of it enters the colon and is metabolized by microorganisms into substances such as benzoic acid, phenylpropionic acid and cinnamic acid before being absorbed. Therefore, after oral administration of CGA, it mainly exists in the form of metabolites in plasma. Antibiotics can affect the normal flora of the colon, which in turn affects the concentration of CGA in plasma.

So, what does honeysuckle extract do?(Honeysuckle Extract Benefits)
1. Cardiovascular protection
Honeysuckle flower extract acts as a free radical scavenger and antioxidant, exerting an important protective effect on the cardiovascular system. Vascular endothelial cell injury is the basis of pathological conditions such as platelet aggregation, coagulation, vascular smooth muscle cells, apoptosis and proliferation, and regulation of vascular tension. Studies have shown that chlorogenic acid has a preventive protective effect on oxidized low-density lipoprotein (ox-LDL)-induced human endothelial cell damage, protects cardiomyocytes from oxidative emergency damage, and inhibits iron ion-induced intracellular microsomes and Lipid peroxidation of mitochondrial membranes effectively protects vascular endothelial cells.
2. Antimutagenic and antitumor effects
Honeysuckle extract powder can prevent tumor diseases. Chlorogenic acid is mainly a pro-oxidant in an alkaline environment, which can induce tumor cells to produce larger DNA fragments and enhance the activity of aromatic hydrocarbon hydroxylase, which is the product of polyaromatic hydrocarbons. An important metabolic enzyme that helps improve the mutagenic effect of tissue cells against polyaromatic compounds.
3. Antibacterial and antiviral effects
Lonicera caprifolium extract can inhibit the growth of Escherichia coli, Staphylococcus aureus, Bacillus subtilis, Micrococcus luteus and Legionella, and inhibit the arylamine acetyltransferase (NAT) in bacteria. Chlorogenic acid powder can effectively inhibit syncytial virus, Coxsackie group B type 3 and adenovirus type 7, etc., and has a strong inhibitory effect on adenovirus type 11.
4. Lipid-lowering effect
Honeysuckle extract can effectively reduce the content of cholesterol and triglyceride in the blood plasma, as well as the level of triglyceride in the liver, and effectively balance the blood lipid level in the body.
5. Anti-leukemia effect
Honeysuckle powder CGA has a weak anti-leukemia effect, inhibits Ber-Abl and c-Abl tyrosine kinases, and induces Ber-Abl-positive cells, such as the apoptosis of Ber-Abl-positive primitive lymphocytes in patients with chronic myeloid leukemia. It can also destroy Ph chromosome-positive chronic myelogenous leukemia cell line K562.
6. Regulate immunity
Organic honeysuckle extract can enhance the proliferation of T cells caused by influenza virus antigens, induce lymphocytes and human peripheral blood leukocytes to produce 7-IFN and a-IFN, activate calcineurin, effectively enhance the phagocytosis of cells, and improve the body's immunity .
7. Lower blood sugar
Chlorogenic acid powder has a hypoglycemic effect, effectively regulates blood sugar levels in the body, regulates insulin secretion, and avoids rapid rise in blood sugar and hyperglycemic diseases.

Can Honeysuckle Extract Treat Bacterial Colds?
Studies have shown that honeysuckle extract has a strong anti-pathogenic effect on Staphylococcus aureus, Staphylococcus albus, Hemolytic Streptococcus, Klebsiella pneumoniae, Neisseria meningitidis, Bacillus typhi, Bacillus paratyphoid, Escherichia coli, Many Gram-positive and Gram-negative bacteria such as Shigella, Proteus, Pertussis, Pseudomonas aeruginosa, Mycobacterium tuberculosis, and Bacillus cholerae have certain antibacterial effects, and can also effectively inhibit various viral infections and enhance T in the body. The phagocytosis of cells and lymphocytes can improve the disease resistance rate of cells and effectively prevent various bacterial infections and viral colds.

Honeysuckle extract for skin:
The main functions of honeysuckle extract in cosmetics and skin care products are whitening and freckle removal, anti-inflammation, and anti-oxidation. It is relatively safe and can be used safely without the risk of causing acne.
Honeysuckle extract contains coffee tannin, which has strong antibacterial and anti-aging effects on the skin; luteolin contained in it has antibacterial and anti-inflammatory effects, has strong permeability to the skin, can penetrate deep into the skin layer, and inhibit hyaluronic acid Enzyme activity, synergistic use with hyaluronidase can prolong the activity of chlorogenic acid, help eliminate free radicals, resist UV damage to the skin, inhibit and eliminate skin pigmentation, especially age spots.

Where Can I Buy Honeysuckle Extract?
Shaanxi Hongda Phytochemistry Co., Ltd. is organic honeysuckle extract factory and honeysuckle extract manufacturer. It has been specialized in plant extracts and API APIs for 30 years. The company is located in the production base of honeysuckle and many plant raw materials---- Shaanxi has the unique Qinling Mountains as a picking place, with an annual production capacity of 8,000 tons, which are exported in large quantities to countries such as the United States, Italy, Japan, Spain, Russia, Vietnam, and Switzerland.

If you have any question about our product,please Contact Us:

Email:duke@hongdaherb.com

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